Cleidocranial Dysplasia - surgically uncovering and bonding multiple impacted permanent teeth | ||||
Egyptian Journal of Oral and Maxillofacial Surgery | ||||
Volume 16, Issue 3, July 2025, Page 137-141 PDF (426.67 K) | ||||
Document Type: Case Report | ||||
DOI: 10.21608/omx.2025.348511.1272 | ||||
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Authors | ||||
Dr. SEEMA SHANTILAL PENDHARKAR ![]() ![]() | ||||
oral and maxillofacial surgery | ||||
Abstract | ||||
Skeletal, craniofacial, and Oro-dental abnormalities are hallmarks of Cleidocranial Dysplasia (CCD), an autosomal dominant bone disorder brought on by a mutation in the CBFA1 gene. People have open fontanelles, hypoplastic/aplastic clavicles, small height, many impacted teeth, delayed eruption of permanent teeth, supernumerary teeth, and retained primary teeth. When this ailment is diagnosed early, the treatment plan that gives these people the best quality of life can be implemented. Notably, CCD patients have been shown to have mutations in the Runx2 gene. Thus, a better understanding of dental development in CCD may result from additional clarification of the molecular process underlying the creation of extra teeth linked to Runx2 mutations. In this case study, a 17-year-old female patient with Cleidocranial Dysplasia had her unerupted maxillary anterior permanent teeth surgically exposed for aesthetic and orthodontic purposes. Clinical follow-up, the patient’s continued therapy, and the family’s understanding and drive are all crucial in these situations. | ||||
Keywords | ||||
Cleidocranial Dysplasia; multiple impacted teeth; supernumerary teeth; hypoplastic/aplastic clavicles | ||||
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