Investigate the Levels of Certain Adipokines in Patients with Diabetes in Kirkuk- Iraq | ||
| Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology | ||
| Volume 17, Issue 2, December 2025, Pages 25-31 PDF (530.16 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/eajbsc.2025.444126 | ||
| Authors | ||
| Diman M. Mahmood1; Haifaa M. Amin1; Sara O. Hassan2; Aras Q. Pirot3 | ||
| 1Sulaimani Polytechnic University, Collage of Health and Medical Technologies, Medical Laboratory Department, Kurdistan, Iraq. | ||
| 2Sulaimani Polytechnic University, Technical Institute of Sulaimani, Radiology department. Kurdistan, Iraq. | ||
| 3Sulaimani Polytechnic University, Technical Institute of Sulaimani, Medical Laboratory Department, Kurdistan, Iraq. | ||
| Abstract | ||
| Background: High blood sugar levels over an extended period are the primary sign of diabetes mellitus (DM), a metabolic disorder that falls under this class. It can be classified as one of the world's major diseases because it affects a large population and comes in two primary varieties: Type I and Type II. Objectives: The current study's goal is to assess many adipokines in patients with diabetes mellitus, including resistine, leptin, adiponectin and Apelin. Material and Methods: 50 patients (31 males and 19 females), age range (35-69) years (mean± SD) (49.7±13.1) years were enrolled in this study. All were consecutively admitted to the clinic at Azadi Teaching Hospital from January to March 2024. All patients had Type 2 Diabetes Mellitus (T2DM) as diagnosed by the physician. This study also included 25 healthy volunteers as a control group. Results: The current outcomes show that the concentration of Adiponectin demonstrated a significant (P <0.05) reduction in Diabetes Mellitus patients compared with healthy subjects. Also, the findings showed that, compared to healthy people, the Apelin concentration in DM patients was significantly (P <0.05) higher. Compared to healthy volunteers, the leptin levels in Diabetes Mellitus patients were significantly (P <0.05) higher. Compared to healthy volunteers, the resistin concentration in DM patients showed a significant (P <0.05) increase. Conclusion: In conclusion, the recent study found that leptin, resistin, and apelin levels were significantly increased in patients with DM compared to healthy people. However, adiponectin level was decreased. | ||
| Keywords | ||
| Adipokines; DM; Leptin; Apelin, Adiponectin | ||
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