Surgical Procedures Versus Catheter Intervention in Management of Adult Aortic Coarctation: A Meta-Analysis | ||||
| The Medical Journal of Cairo University | ||||
| Volume 93, Issue 06, June 2025, Page 625-633 PDF (207.53 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2025.444263 | ||||
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| Author | ||||
| HASSAN M.E. YOUSSEF MOFTAH, M.D.*; ASHRAF A. EL MIDANY, M.D.*; AYMAN A. DOGHISH, M.D.*; AHMED M. FARGHALY, M.D.* and MOHAMED A. GAD, M.Sc.** | ||||
| The Department of Cardiothoracic Surgery, Faculty of Medicine, Ain Shams University* and M.B.B.Ch., Faculty of Medicine, Minia University** | ||||
| Abstract | ||||
| Background: Coarctation of aorta refers to constriction of aorta, typically located just distal to left subclavian artery. Aim of Study: This study aimed to evaluate current litera-tures for the outcomes of surgery versus catheter intervention in treatment of adult patients of coarctation. Material and Methods: Systematic review, meta-analysis encompass randomized clinical trials, cohort studies, cross-sec-tional research. Methodological quality of each study was rig-orously evaluated, clarity in outcome measures, appropriate-ness in statistical analysis to ensure robustness of findings. Results: A meta-analysis of post-intervention outcomes after aortic coarctation repair found that catheter intervention had significantly lower mortality rates and persistent hyper-tension compared to surgical repair. Aneurysm formation fol-lowing catheter intervention was rare, with no heterogeneity. Re-intervention for recoarctation was slightly more common in catheter cases (10%) than in surgical repair (7.6%), with mod-erate heterogeneity. The findings suggest catheter intervention may be a preferable option due to lower mortality and persistent hypertension, though with a slightly higher need for re-inter-vention. The study highlights the need for more comprehensive and effective surgical interventions in aortic coarctation repair. Conclusion: Surgical repair and catheter-based interven-tions have positive long-term outcomes, but have unique chal-lenges. Surgical repair was related with persistent hypertension, despite fact that it has a higher mortality rate. Catheter-based interventions were less invasive, they were related with a high-er risk of aneurysm formation, re-interventions. | ||||
| Keywords | ||||
| Adult aortic coarctation; Catheter intervention; Surgical procedures | ||||
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