ROLE OF SUSCEPTIBILITY WEIGHTED IMAGING IN GLIAL TUMORS GRADING | ||
| ALEXMED ePosters | ||
| Article 1, Volume 7, Issue 3, July 2025, Pages 24-25 | ||
| Document Type: Preliminary preprint short reports of original research | ||
| DOI: 10.21608/alexpo.2025.407738.2230 | ||
| Authors | ||
| Tarek Mohamed Rashad Saleh1; Amal Shawky Ismail2; Basma Abdel-Azim Kamel Ahmed* 3 | ||
| 1Department of Radiodiagnosis, Faculty of Medicine, University of Alexandria, Alexandria, Egypt. | ||
| 2Radiodiagnosis and Intervention, Medicine, Alexandria, Alexandria, Egypt | ||
| 3Department of Radiodiagnosis and Intervention, Faculty of Medicine, Alexandria University | ||
| Abstract | ||
| 1. Introduction SWI is very effective at detecting neovascularity (which includes venous blood and deoxygenated hemoglobin), hemorrhage, and calcification, making it a crucial modality for evaluating the internal composition of gliomas. The intra-tumoral susceptibility signal (ITSS) acts as a non-invasive imaging marker for neovascularity. Research indicates that ITSS is positively correlated with increased cerebral blood volume (CBV) seen on MR perfusion imaging and is also linked to tumor grade in histopathological assessments. 2. Aim This study aimed to assess the utility and effectiveness of ITSS grading in glioma classification and to investigate whether the level of intratumoral susceptibility signal intensity (ITSS) observed on high-resolution SWI correlates with findings from dynamic susceptibility contrast (DSC) perfusion MRI, MR spectroscopy, and histopathological analysis. 1. Patient and Methods PATIENTS:The study prospectively and retrospectively enrolled thirty-six (36) patients referred to the Radiology Department of Alexandria Main University Hospital for assessment of brain glial tumors in the period between December 2023 and January 2025. METHODS: All patients were subjected to: Full history taking [demographic data, general medical history focusing upon the manifestations of focal neurological deficit, Symptoms of increased intracranial pressure and seizures and surgical historyincludes screening for cardiac pacemakers, cochlear implants, or other metallic implants incompatible with MRI, Pre-contrast MRI brain series, SWI, Post-contrast T1WI, DSC, MRI spectroscopy, Histopathology and CT brain if needed. | ||
| Keywords | ||
| SWI; ITSS; Gliomas | ||
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