Impact of Diabetic Retinopathy Treatment Modalities on Vision-Related Quality of Life: A Comparative Study Using NEI VFQ-25 | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 116, Volume 100, Issue 1, July 2025, Page 3354-3360 PDF (663.91 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2025.444601 | ||||
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| Abstract | ||||
| Background: Diabetic retinopathy (DR) is a leading cause of visual impairment and affects patients' quality of life. Understanding the impact of different treatments on vision-related quality of life (VR-QOL) is essential for optimizing care. Objective: To assess the effect of different lines of diabetic retinopathy treatment on patients’ (VR-QOL) using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25). Patients and Methods: This prospective quasi-experimental study was conducted in Mansoura Ophthalmology Center over 6 months on 200 diabetic retinopathy patients, in which 50 patients received laser photocoagulation, 50 patients received anti-VEGF treatment, 50 received intravitreal steroids, and vitrectomy was planned for 50 patients. The NEI VFQ-25 was fulfilled by all patients before treatment and 1 month and 6 months after treatment. The results were compared to the baseline in each group. Results: Themean age of the included patients was 57.58±7.38 years with female predominance (54.5%). Patients who underwent vitrectomy had significantly higher mean age compared to patients who received laser or anti-VEGF therapy and most of them came from rural areas. Most of the subscales and total score showed significant improvement from baseline to 1- month and 6- month post treatment in total cohort. The most significant improvement was noted in the vitrectomy group followed by the anti-VEGF group. Conclusion: All treatment modalities led to significant improvements in VR-QOL with varying degrees. Vitrectomy demonstrated the most substantial effect, particularly in advanced DR, followed by intravitreal anti-VEGF. The study highlights the importance of tailored interventions based on disease severity. | ||||
| Keywords | ||||
| Diabetic retinopathy; Vision-Related Quality of Life; Laser photocoagulation; Anti-VEGF; IVTA | ||||
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