Study of Some Types of Bacteria and application of biological activity for some new Heterocyclic Compounds containing nitrogen Derivatives | ||||
| Journal of Bioscience and Applied Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 31 July 2025 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jbaar.2025.360107.1153 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Eman Abdul Wahab1; Rajaa Abdulameer Ghafil2; mohauman M majeed  3
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| 1Faculty of Medicine, Department of biochemistry,Jaber ibn Hayyan for Medical and pharmaceutical Sciences University, Iraq. | ||||
| 2Department of chemistry ,College Education for Girls, University of Kufa, Iraq. | ||||
| 3kufa | ||||
| Abstract | ||||
| Abstract: This broadside including prepared of certain bio heterocyclic multifaceted derivatives starting:6-bromo- 2-hydroxy napthaldehyde ,by the reaction between of 2-amino-5-bromo pyrimidine with 6-bromo- 2-hydroxy napthaldehyde , to produce shiff base derivative (S), the latter compound was used as an important substance to prepare Six new heterocyclic derivatives that have pyrimidine ring. Also, newly synthesized compounds were characterized by spectral data (FTIR, ¹H NMR, ¹³C NMR), all the prepared derivatives were studied on four types of bacteria (Staphylococcus aurous and Escherichia coli Enterococcus faecalis, pseudomonas aeruginosa), by paper technique disks. Biological capacity tests for these derivatives revealed favorable findings.Pyrimidine is widely found in nature as a component of nucleic acids (cytosine, thymine, and uracil) and many other natural and synthetic compounds, including pharmaceuticals, and has become known over time as a powerful pharmacophore(1). Also Pyrimidine can be considered cyclic amines(2), Pyrimidine is also known as 1,3-diazine. It is the fundamental substance of a large group of heterocyclic compounds and plays a vital role in many biological processes (3). Schiff bases are an important group of organic medicinal chemical compounds, there are contain an | ||||
| Keywords | ||||
| Bacteria; microwave irradiation; Schiff beses; oxazepine; biological activity | ||||
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