Study of Some Types of Bacteria and application of biological activity for some new Heterocyclic Compounds containing nitrogen Derivatives | ||
| Journal of Bioscience and Applied Research | ||
| Article 9, Volume 11, Issue 3, September 2025, Pages 823-836 PDF (2.21 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jbaar.2025.360107.1153 | ||
| Authors | ||
| Eman Abdul Wahab1; Rajaa Abdulameer Ghafil2 | ||
| 1Faculty of Medicine, Department of biochemistry,Jaber ibn Hayyan for Medical and pharmaceutical Sciences University, Iraq. | ||
| 2Department of chemistry ,College Education for Girls, University of Kufa, Iraq. | ||
| Abstract | ||
| This broadside includes a preparation of certain bioheterocyclic multifaceted derivatives starting: 6-bromo-2-hydroxy napthaldehyde, by the reaction between 2-amino-5-bromo pyrimidine with 6-bromo-2-hydroxy napthaldehyde, to produce a Schiff base derivative (S). The latter compound was used as an important substance to prepare six new heterocyclic derivatives that have a pyrimidine ring. Also, newly synthesized compounds were characterized by spectral data (FTIR, ¹H NMR, ¹³C NMR), and all the prepared derivatives were studied on four types of bacteria (Staphylococcus aureus and Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa), by paper technique disks. Biological capacity tests for these derivatives revealed favorable findings. | ||
| Keywords | ||
| Bacteria; microwave irradiation; Schiff beses; oxazepine; biological activity | ||
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