Laparoscopic and Open Radical Cystectomy: Comparative Short-Term Outcomes from a Single-Center Experience | ||
| SECI Oncology Journal | ||
| Volume 13, Issue 3, July 2025, Pages 186-197 PDF (450.39 K) | ||
| DOI: 10.21608/secioj.2025.445235 | ||
| Abstract | ||
| Background: Bladder cancer accounts for 3.0% of new cancer cases and 2.1% of cancer-related deaths. The standard treatment for bladder cancer is open radical cystectomy (ORC) with pelvic lymphadenectomy. But associated with morbidity exceeds 50% in specialized centers. Laparoscpic radical cystectomy (LRC) has lower rate of complications while achieving oncological outcomes comparable to open surgery. Objective: To compare short-term outcomes of patients with bladder cancer submitted to ORC and LRC as regard oncologic safety, intraoperative and postoperative morbidity and mortality Methods: Retrospective analysis involved 309 patients with bladder cancer underwent either open or laparoscopic radical cystectomy. the patients were divided into two groups: • Group 1: 89 patients who had (LRC). • Group 2: 220 patients who had (ORC). Results: Our study demonstrated notable differences in outcomes between the two methods. The open technique associated with greater intraoperative blood loss, higher need for blood transfusions and shorter operating time, whereas the laparoscopic procedure significantly reduced bleeding, shorter hospital stay, quicker overall recovery. Both methods exhibited similar rates of minor and major complications, with no significant differences. Pathological evaluations, including tumor staging, lymph node retrieval, and margin status, were equivalent, indicating that the laparoscopic approach maintains oncologic safety while offering better perioperative benefits than the open technique. Conclusion: In conclusion, Laparoscopic radical cystectomy offers a safe minimally invasive alternative to open surgery and LRC is oncologically not inferior to ORC. | ||
| Keywords | ||
| bladder cancer; LRC; ORC | ||
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