Descriptive data of patients with SBP in Minia university hospital

Ibrahim, Sharehan AbdElrahman; Ahmed, Elham; Aly, Lamia Hamdy; Mostafa, Alaa M; Abozeid, Mohammed Roshdy; Hassan, Hatem Ahmed

doi:10.21608/mjmr.2025.400061.2018

	Descriptive data of patients with SBP in Minia university hospital
Minia Journal of Medical Research
Articles in Press, Accepted Manuscript, Available Online from 03 August 2025
Document Type: Original Article
DOI: 10.21608/mjmr.2025.400061.2018
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Authors
Sharehan AbdElrahman Ibrahim¹; Elham Ahmed¹; Lamia Hamdy Aly²; Alaa M Mostafa ³; Mohammed Roshdy Abozeid ⁴; Hatem Ahmed Hassan¹
¹Internal medicine department, faculty of medicine, Minia university, Minia, Egypt
²Department of clinical pathology, faculty of medicine, minia university ,Minia, Egypt.
³Department of tropical medicine, faculty of medicine, Minia university, Minia, Egypt
⁴Internal medicine department, faculty of medicine, Minia university, Minia, Egypt.
Abstract
Background: Spontaneous bacterial peritonitis (SBP) is a frequent and serious complication in cirrhotic patients with ascites. Early recognition of clinical and laboratory markers is crucial for timely diagnosis and management. Objective: This study aimed to evaluate the clinical and laboratory characteristics associated with SBP among patients with liver cirrhosis and ascites admitted to Minia University Hospital. Methods: A prospective observational study was conducted involving 150 patients aged 18–65 years with liver cirrhosis and ascites. Participants were divided into three groups: culture-positive SBP, culture-negative SBP, and non-SBP. Exclusion criteria included patients with secondary peritonitis, hepatocellular carcinoma, prior antibiotic use, and hepatorenal syndrome. Results: Baseline demographics and liver disease severity (age, sex, HCV/HBV status, and Child-Pugh score) did not differ significantly between SBP and non-SBP groups. However, SBP patients showed a significantly higher frequency of abdominal pain (57% vs. 0%) and fever (47% vs. 0%) (p<0.001). Laboratory findings also revealed elevated total leukocyte and neutrophil counts in SBP patients (p<0.01). Conclusion: Abdominal pain, fever, and elevated leukocyte and neutrophil counts are strongly associated with SBP in cirrhotic patients with ascites.
Keywords
Spontaneous bacterial peritonitis; liver cirrhosis; descriptive data


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