Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds
Eldehn, A., El-Badrawy, A., EL-kheshen, A., Abdelhamid, A., Yousef, A. (2025). Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds. EKB Journal Management System, (), -. doi: 10.21608/ejentas.2025.391390.1847
Ahmed Eldehn; Amr El-Badrawy; Ahmed Mohammed Ragheb EL-kheshen; Asmaa Abdelhamid; Ahmed Yousef. "Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds". EKB Journal Management System, , , 2025, -. doi: 10.21608/ejentas.2025.391390.1847
Eldehn, A., El-Badrawy, A., EL-kheshen, A., Abdelhamid, A., Yousef, A. (2025). 'Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds', EKB Journal Management System, (), pp. -. doi: 10.21608/ejentas.2025.391390.1847
Eldehn, A., El-Badrawy, A., EL-kheshen, A., Abdelhamid, A., Yousef, A. Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds. EKB Journal Management System, 2025; (): -. doi: 10.21608/ejentas.2025.391390.1847

Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds

Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Articles in Press, Accepted Manuscript, Available Online from 04 August 2025  XML
Document Type: Original Article
DOI: 10.21608/ejentas.2025.391390.1847
View on SCiNiTO View on SCiNiTO
Authors
Ahmed Eldehn1; Amr El-Badrawy1; Ahmed Mohammed Ragheb EL-kheshen2; Asmaa Abdelhamid3; Ahmed Yousef email orcid 4
1Otolaryngology Department, Kasr Al-Aini, Faculty of Medicine, Cairo University, EGYPT.
2Otolaryngology Department, Kasr Al-Aini, Faculty of Medicine, Cairo University, EGYPT
3ENT department, kasr alaini hospital, Cairo University
4Otolaryngology department faculty of medicine Cairo university
Abstract
Background: To verify the effectiveness of platelet-rich plasma (PRP) injection on voice quality in patients with glottic insufficiency. A prospective study was conducted on 20 adult patients of both genders aged above 20 years old with glottic insufficiency candidate for (PRP) injection into vocal fold using fiber-optic laryngoscope under local anesthesia.
Results: No significant improvement was found between fundamental frequency, jitter %, noise to harmonic ratio and maximum phonation time among pre-injection, after month and after 3 months but shimmer % showed a statistically significant decrease after 3 months of follow-up from pre-injection while 1 month showed no statistically significant difference from pre-injection.
Conclusion: (PRP) is safe to use as an option for treatment of glottic insufficiency . The risk-benefit ratio makes even small or partial gains advantageous. Significant decrease in shimmer% was observed after 3 months following PRP injection. Additionally, other acoustic parameters were improved after one month and 3 months of follow-up but with no statistically significant differences compared with the baseline before the injection.
Keywords: Platelet-rich plasma, vocal fold atrophy, voice analysis.
Keywords
Platelet-rich plasma; vocal fold atrophy; voice analysis
Statistics
Article View: 25