Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds
Eldehn, A., El-Badrawy, A., EL-kheshen, A., Abdelhamid, A., Yousef, A. (2025). Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds. EKB Journal Management System, (), -. doi: 10.21608/ejentas.2025.391390.1847
Ahmed Eldehn; Amr El-Badrawy; Ahmed Mohammed Ragheb EL-kheshen; Asmaa Abdelhamid; Ahmed Yousef. "Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds". EKB Journal Management System, , , 2025, -. doi: 10.21608/ejentas.2025.391390.1847
Eldehn, A., El-Badrawy, A., EL-kheshen, A., Abdelhamid, A., Yousef, A. (2025). 'Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds', EKB Journal Management System, (), pp. -. doi: 10.21608/ejentas.2025.391390.1847
Eldehn, A., El-Badrawy, A., EL-kheshen, A., Abdelhamid, A., Yousef, A. Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds. EKB Journal Management System, 2025; (): -. doi: 10.21608/ejentas.2025.391390.1847

Injection of Platelet-Rich Plasma in patients with Atrophic Vocal Folds

Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Articles in Press, Accepted Manuscript, Available Online from 04 August 2025
Document Type: Original Article
DOI: 10.21608/ejentas.2025.391390.1847
Authors
Ahmed Eldehn1; Amr El-Badrawy1; Ahmed Mohammed Ragheb EL-kheshen2; Asmaa Abdelhamid3; Ahmed Yousef* 4
1Otolaryngology Department, Kasr Al-Aini, Faculty of Medicine, Cairo University, EGYPT.
2Otolaryngology Department, Kasr Al-Aini, Faculty of Medicine, Cairo University, EGYPT
3ENT department, kasr alaini hospital, Cairo University
4Otolaryngology department faculty of medicine Cairo university
Abstract
Background: To verify the effectiveness of platelet-rich plasma (PRP) injection on voice quality in patients with glottic insufficiency. A prospective study was conducted on 20 adult patients of both genders aged above 20 years old with glottic insufficiency candidate for (PRP) injection into vocal fold using fiber-optic laryngoscope under local anesthesia.
Results: No significant improvement was found between fundamental frequency, jitter %, noise to harmonic ratio and maximum phonation time among pre-injection, after month and after 3 months but shimmer % showed a statistically significant decrease after 3 months of follow-up from pre-injection while 1 month showed no statistically significant difference from pre-injection.
Conclusion: (PRP) is safe to use as an option for treatment of glottic insufficiency . The risk-benefit ratio makes even small or partial gains advantageous. Significant decrease in shimmer% was observed after 3 months following PRP injection. Additionally, other acoustic parameters were improved after one month and 3 months of follow-up but with no statistically significant differences compared with the baseline before the injection.
Keywords: Platelet-rich plasma, vocal fold atrophy, voice analysis.
Keywords
Platelet-rich plasma; vocal fold atrophy; voice analysis
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