The Prognosis Of Premature Newborn Who Suffer From Respiratory Distress Syndrome With And Without Patent Ductus Arteriosus | ||
| Zagazig University Medical Journal | ||
| Volume 31, Issue 9, September 2025, Pages 4582-4587 PDF (1.04 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2025.396971.4018 | ||
| Authors | ||
| Islam Abdelrasheed Algaafarey* 1; Amr Megahed Abou El-Naga2; Tareq Abdelrahman Mohammed3 | ||
| 1Resident of pediatrics, Hurghada General Hospital, Hurghada, Egypt. | ||
| 2Professor of pediatrics and pediatric cardiology, Faculty of Medicine, Zagazig University, Zagazig, Egypt. | ||
| 3Professor of pediatrics, Faculty of Medicine, Zagazig University, Zagazig, Egypt. | ||
| Abstract | ||
| Background: The prognosis of premature newborns with respiratory distress syndrome (RDS) depends on factors such as gestational age, birth weight, infection, requirement for respiratory support and diagnosis of a patent ductus arteriosus (PDA). The aim of our study was to assess the morbidity and mortality of premature newborn who suffer from RDS and PDA and study the clinical, microbiological & echocardiographic aspects of those patients and demonstrate the differences in clinical profile, microbiology, echocardiography and clinical outcome between premature newborn who suffer from RDS and PDA and those who have RDS without PDA. Methods: This retrospective observational study was carried out on 25 premature neonates with RDS requiring intubation and surfactant therapy, RDS and PDA identified on echocardiography. Patients were assigned into two groups: Group I: admitted with RDS with PDA and Group II: admitted with RDS without PDA during the same period. Results: 1-min and 5-min Apgar score, hemoglobin, white blood cells, pH, HCO3, O2 saturation, and PaO2 were significantly lower in Group 1 than Group 2 as (P value <0.05). while Na and PaCO2 were significantly higher in Group 1 than Group 2. Mortality and morbidity were insignificantly different between the two groups. Conclusion: RDS and PDA preterm infants show a lower Apgar score, hemoglobin level, and O2 saturation in comparison to RDS without PDA preterm infants. Mortality and morbidity are insignificantly different between RDS and PDA preterm infants and RDS without PDA preterm infants’ group. | ||
| Keywords | ||
| Premature; Distress; Ductus; Arteriosus; Newborn | ||
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