Study of The Safety and Efficacy of Different Esomeprazole Containing Regimens for Eradication of Helicobacter Pylori Infection | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 2, February 2025, Pages 177-182 PDF (326.21 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aimj.2025.446436 | ||
| Authors | ||
| Atef Abu Al-Futouh Ibrahim1; Abdelaleem Abdelaleem Aly Elgendy2; Mohamed Aly AbdelKhalek Alboraie1; Ibrahim Mohamed Shebl Elsaidy* 1 | ||
| 1Internal Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||
| 2Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Background: One of the most prevalent chronic bacterial illnesses affecting humans is Helicobacter pylori (H. pylori). Helicobacter pylori has colonized more than 50% of the global population. Infection with Helicobacter pylori can affect as many as 80% of the population in some nations, such as Egypt; however, this number varies widely around the globe. Aim and objectives: To determine which esomeprazole-containing regimens are safest and most effective in eliminating H. pylori infection. Patients and methods: This is a prospective observational study carried out on 120-patients. The material of the present study included H. Pylori patients who were recruited form Al-Hussein Hospital, internal medicine outpatient clinics from April 2023 and April2024. Results: H. pylori eradication rate after esomeprazole-based regimen was 70.8%. Eradication rate did not significantly differ between different esomeprazole-based regimens. Also, patients reported adverse events had significantly lower eradication rate of H. pylori. Conclusion: The overall eradication rate of H. pylori using esomeprazole-based regimens was 70.8%, indicating moderate efficacy across different treatment protocols. The eradication rates were similar across all five esomeprazole-based regimens, suggesting that the efficiency of the antibiotic combinations used was not significantly different. | ||
| Keywords | ||
| Esomeprazole; H. pylori; Eradication; Infection; Regimens | ||
|
Statistics Article View: 27 PDF Download: 16 |
||
