Study of The Safety and Efficacy of Different Esomeprazole Containing Regimens for Eradication of Helicobacter Pylori Infection
Ibrahim, A., Elgendy, A., Alboraie, M., Elsaidy, I. (2025). Study of The Safety and Efficacy of Different Esomeprazole Containing Regimens for Eradication of Helicobacter Pylori Infection. EKB Journal Management System, 2025(2), 177-182. doi: 10.21608/aimj.2025.446436
Atef Abu Al-Futouh Ibrahim; Abdelaleem Abdelaleem Aly Elgendy; Mohamed Aly AbdelKhalek Alboraie; Ibrahim Mohamed Shebl Elsaidy. "Study of The Safety and Efficacy of Different Esomeprazole Containing Regimens for Eradication of Helicobacter Pylori Infection". EKB Journal Management System, 2025, 2, 2025, 177-182. doi: 10.21608/aimj.2025.446436
Ibrahim, A., Elgendy, A., Alboraie, M., Elsaidy, I. (2025). 'Study of The Safety and Efficacy of Different Esomeprazole Containing Regimens for Eradication of Helicobacter Pylori Infection', EKB Journal Management System, 2025(2), pp. 177-182. doi: 10.21608/aimj.2025.446436
Ibrahim, A., Elgendy, A., Alboraie, M., Elsaidy, I. Study of The Safety and Efficacy of Different Esomeprazole Containing Regimens for Eradication of Helicobacter Pylori Infection. EKB Journal Management System, 2025; 2025(2): 177-182. doi: 10.21608/aimj.2025.446436

Study of The Safety and Efficacy of Different Esomeprazole Containing Regimens for Eradication of Helicobacter Pylori Infection

Al-Azhar International Medical Journal
Volume 2025, Issue 2, February 2025, Page 177-182  XML PDF (326.21 K)
Document Type: Original Article
DOI: 10.21608/aimj.2025.446436
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Authors
Atef Abu Al-Futouh Ibrahim1; Abdelaleem Abdelaleem Aly Elgendy2; Mohamed Aly AbdelKhalek Alboraieorcid 1; Ibrahim Mohamed Shebl Elsaidy* 1
1Internal Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
2Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Abstract
Background: One of the most prevalent chronic bacterial illnesses affecting humans is Helicobacter pylori (H. pylori). Helicobacter pylori has colonized more than 50% of the global population. Infection with Helicobacter pylori can affect as many as 80% of the population in some nations, such as Egypt; however, this number varies widely around the globe.
Aim and objectives: To determine which esomeprazole-containing regimens are safest and most effective in eliminating H. pylori infection.
Patients and methods: This is a prospective observational study carried out on 120-patients. The material of the present study included H. Pylori patients who were recruited form Al-Hussein Hospital, internal medicine outpatient clinics from April 2023 and April2024.
Results: H. pylori eradication rate after esomeprazole-based regimen was 70.8%. Eradication rate did not significantly differ between different esomeprazole-based regimens. Also, patients reported adverse events had significantly lower eradication rate of H. pylori.
Conclusion: The overall eradication rate of H. pylori using esomeprazole-based regimens was 70.8%, indicating moderate efficacy across different treatment protocols. The eradication rates were similar across all five esomeprazole-based regimens, suggesting that the efficiency of the antibiotic combinations used was not significantly different.
Keywords
Esomeprazole; H. pylori; Eradication; Infection; Regimens
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