Endometrial Ablation vs Levonorgestrel Therapy in Management of Simple Endometrial Hyperplasia in Perimenopausal Women with Abnormal Uterine Bleeding | ||||
| Al-Azhar International Medical Journal | ||||
| Volume 2025, Issue 2, February 2025, Page 263-268 PDF (408.1 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/aimj.2025.446450 | ||||
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| Authors | ||||
| Samir Abdallah Ali; Ibrahim Mohamed Ibrahim Abo eldahab; Mahmoud Fawzy Mahmoud Darwish Abu Ghoniem* | ||||
| Obstetrics and Gynecology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Variations from regular menstrual cycles that continue for at least six months after menarche in reproductive-aged women who are not pregnant are referred to as abnormal uterine hemorrhage. At least 30% of reproductive-aged women seek medical attention for this issue. Aim and objectives: To evaluate the efficacy of endometrial ablation vs levonorgestrel treatment for the treatment of uncomplicated endometrial hyperplasia in postmenopausal women experiencing abnormal vaginal bleeding. Patients and methods: One hundred participants were included in this prospective interventional trial from November 2023 to September 2024 from the Al-Azhar University Hospitals' outpatient obstetrics and gynecology clinics. The systematic random method was used for sample collection. Results: Both treatment groups showed a notable decrease in endometrial thickness (p < 0.001). In contrast to Group 2, which had levonorgestrel medication, Group 1, which underwent endometrial ablation, demonstrated a more significant reduction. The mean rank for endometrial thickness pre-treatment was 44.78 for Group 1 and 56.22 for Group 2, while post-treatment, it was 31.74 for Group 1 and 69.26 for Group 2. This indicates that endometrial ablation was more effective in reducing endometrial thickness. Conclusion: Our study showed that there were fewer adverse effects and better results in reducing endometrial thickness and controlling menstrual blood loss. While endometrial ablation showed better outcomes in our study, it is a surgical procedure that permanently affects the endometrium, which may not be suitable for all patients. | ||||
| Keywords | ||||
| Endometrial ablation; Uterine bleeding; Perimenopausal women; Levonorgestrel therapy | ||||
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