Chemical Composition of Launaea spinosa Methanolic Extract and Its Potential Antioxidant and Antimicrobial | ||||
| Mansoura Journal of Biology | ||||
| Volume 68, Issue 1, March 2024, Page 42-47 PDF (893.95 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjb.2024.446683 | ||||
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| Authors | ||||
Basma S. El-Nabawy; Hoda M. Soliman; Yasser A. El-Amier  
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| Botany Department, Faculty of Science, Mansoura University, Mansoura - 35516, Egypt | ||||
| Abstract | ||||
| Launaea plants, which are members of the Asteraceae family, are used in ethnomedicine to address various health conditions. The medicinal properties of Launaea spinosa are used for the treatment of various ailments. The study aimed to conduct preliminary phytochemical screening of crude extracts of L. spinosa and evaluate its antioxidant and antibacterial potential. Above-ground parts of L. spinosa were collected from Wadi Hagoul in the Eastern desert of Egypt. Phenolic, flavonoids, alkaloids, saponins and tannins were estimated in the extract. Antioxidant activity was evaluated using DPPH assay. The extract showed antioxidant activity ranging from 13.08% at 100 mg/mL to 72.05% at 1000 mg/mL with IC50 value of 59.66 mg/mL. Antibacterial activity was tested against Gram negative and positive bacteria. The extract showed antibacterial activity against most of the tested bacterial isolates. The study concluded that L. spinosa extract contains bioactive compounds and has potential as a natural antioxidant and antibacterial. | ||||
| Keywords | ||||
| Launaea; Asteraceae; DPPH; Antimicrobial; Phytochemical | ||||
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