Left Ventricle Pressure Strain Loop as Predictor of Left Ventricular Function Recovery in Patients with Acute Coronary Syndrome | ||||
| Al-Azhar International Medical Journal | ||||
| Volume 2025, Issue 2, February 2025, Page 282-287 PDF (447.52 K) | ||||
| Document Type: Original Article | ||||
| DOI: /10.21608/aimj.2025.446468 | ||||
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| Authors | ||||
| Abd-Elmohssen Mostaffa Abdo; Ahmed Said Abd-ElAziz; Ahmed Mamdouh Abd-Elmotaleb | ||||
| Cardiology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Acute coronary syndrome (ACS) is among the primary reasons for morbidity and mortality worldwide. Aim: To detect the myocardial stunning recovery in cases with ACS after revascularization with a non-invasive LV pressure strain loop (PSL) as a novel technique for quantitative assessment of myocardial work instead of traditional ejection fraction. Patients and methods: This was a prospective cohort study that enrolled 50 consecutive cases who have been presented by ACS for PCI, either STEMI or NSTE-ACS, managed with primary percutaneous coronary intervention (PCI) and treatment that is dependent on medical guidelines. Results: At monitoring, there were statistically significant differences in ejection fraction, global work index, global work efficiency, and LV global longitudinal strain in comparison to the values, with p-values of 0.005, 0.005, 0.001, 0.005, 0.001, 0.005, and 0.05, respectively. ROC curve analysis proved good discriminating power of the myocardial work index between LVEF <40% and >40%, where the area under the ROC curve (AUC) = 0.832 with SE 0.024 (95% Confidence interval 0.712–0.892. Z statistic = 5.286, p < 0.001. Cutoff point <800 with sensitivity = 87.5% and specificity = 78.8%. Conclusion: We concluded that left ventricular PSL may be considered a novel non-invasive method for the quantitative evaluation of myocardial work and recovery of myocardial stunning in cases with acute coronary syndrome after revascularization instead of traditional ejection fraction. | ||||
| Keywords | ||||
| LV pressure strain loop; LV function recovery; patient with ACS | ||||
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