Management of Vasospasm after Aneurysmal Subarachnoid Hemorrhage | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 145, Volume 100, Issue 1, July 2025, Page 3549-3557 PDF (700.91 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2025.446807 | ||||
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| Abstract | ||||
| Background:The loss of productive life-years after subarachnoid haemorrhage (SAH) is similar in magnitude to that of ischemic stroke.Cerebral vasospasm (VSP) is one of the complications of SAH which is, narrowing of the intracranial arteries several days after an aneurysmal SAH.Objective: This work aimed to assess the different management modalities of cerebral VSP which is a common complication of aneurysmal SAH. Methods:This prospective study included 20 patients with aneurysmal SAH admitted to Neurosurgery Department, Tanta University Hospitals. For patients with vasospasm, Nimodipine was used, which is safe, cost-effective & decreases the risk of poor result & secondary ischemia. It is used prophylactically in all studied cases with SAH. Nimodipine is given either orally or continuous infusion. Endovascular techniques frequently play a role in the aggressive treatment of vasospasm as intra-arterial infusion of vasodilators (Nimodipine). Results: There was a significant negative relationship among Modified fisher score & Glasgow coma scale (GCS) score on admission (r=-0.559, P=0.010), indicating that increasing Modified fisher score on admission is associated with lower GCs.The mean modified Rankin scale (MRS) improved over time from 0.80 ± 1.54 at 2 weeks to 0.55 ± 1.05 at 3 months and further to 0.20 ± 0.52 at 6 months and this difference was statistically significant (p=0.008). MRS score significantly improved with time (P=0.034). Conclusions: VSP following aneurysmal SAH can be devastating and thus prevention and treatment are crucial. Nimodipine is an effective therapy for managing VSP following aneurysmal SAH & endovascular nimodipine was effective for treatment and prevention of vasospasm. | ||||
| Keywords | ||||
| Management; Vasospasm; Aneurysmal subarachnoid hemorrhage | ||||
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