CORRELATIONS AND IL6 LEVEL AMONG SOME BLASTOCYSTIS HOMINIS INFECTED ADOLESCENTS IN FAYOUM GOVERNORATE | ||||
| Journal of the Egyptian Society of Parasitology | ||||
| Volume 55, Issue 2, August 2025, Page 243-250 PDF (413.33 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jesp.2025.447402 | ||||
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| Authors | ||||
Faten Ahmed Mahmoud Mohamed  1; AYA A. H. EL-NAGGAR2
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| 1Department of Medical Parasitology, Faculty of Medicine, Fayoum University, Egypt. | ||||
| 2Department of Medical Parasitology, Faculty of Medicine, Fayoum University, Egypt | ||||
| Abstract | ||||
| Blastocystis is a global protozoan affects the gastrointestinal tract of man and animals. It is frequently observed in human stool samples. The study evaluated Blastocystis hominis in 110 stool samples by Iodine smears, Trichrome staining, and Jones’ culture, between IL6 and infec tion. Microscopic smears and Trichrome staining detected 21and 35 positive cases, with sensi tivity of 50%, and 71.43% and specificity of 100% and 92.65% respectively. Culture method, used as diagnostic test identified more number of positive cases (42 cases). A significant asso ciation was found between infection and the presence of pets (p=0.03). Diarrhea (71.4%; p=0.01), flatulence (45.2%; p=0.01), vomiting (42.9%; p=0.002), and nausea (40.5%; p=0.001) were the patients' symptoms. The IL-6 concentration in stool and plasma positive samples was significantly elevated in patients compared to negative control (P <0.001). These results indi cating that systemic inflammation is related to Blastocystis infection and highlighted the im portance of the complementary use of microscopy, Trichrome stain, and culture techniques in the detection of Blastocystis infection. | ||||
| Keywords | ||||
| Fayoum University; Blastocystis hominis; Stained smears; Stained culture; IL-6 | ||||
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