Evaluation of Prevalence and Effect of Hypophosphatemia on Postoperative Outcomes in Open Heart Surgeries | ||
| Benha Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 13 August 2025 PDF (744.08 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.374051.2360 | ||
| Authors | ||
| Yousry E. Rezk1; Moataz E. Rezk1; Hossam El Din A. Abd El Moneim* 2; Ahmed I. Sobeih3 | ||
| 1Professor of Cardiothoracic Surgery, Faculty of Medicine, Benha University | ||
| 2(M.B.B.CH. Faculty of Medicine, Benha University) | ||
| 3Lecturer of Critical Care Medicine, Faculty of Medicine, Benha University | ||
| Abstract | ||
| Background: Hypophosphatemia is a common yet under-recognized complication following open-heart surgery, potentially impacting postoperative outcomes. Despite its reported association with prolonged mechanical ventilation (MV), ICU stay, and increased morbidity, its incidence and effects remain inconsistently described. Objectives: To establish the incidence of postoperative hypophosphatemia and assess its impact on MV duration, ICU stay, cardioactive drug support, arrhythmia, and mortality. Methods: A prospective case-control study was performed on 100 cases admitted to the Cardiac Surgery ICU after elective open-heart surgery at Benha University Hospitals. Patients were categorized into hypophosphatemic and normophosphatemic groups. Perioperative parameters, laboratory findings, and clinical outcomes were analyzed. Results: Postoperative hypophosphatemia incidence was 40% immediately after surgery and 50% on day one. The hypophosphatemic group had significantly longer ventilation (16.78±3.85 vs. 5.9±2.87 hrs., p<0.001), ICU stay (4.53±1.15 vs. 2.22±0.94 days, p<0.001), hospital stay (7.4±1.65 vs. 5.25±1.2 days, p<0.001), and drain duration (41.43±13.07 vs. 28.98±9.2 hrs., p<0.001). IABP use (15% vs. 0%, p=0.002), re-intubation (12.5% vs. 0%, p=0.005), and arrhythmia (10% vs. 0%, p=0.021) were significantly higher. Mortality was higher in hypophosphatemic patients (7.5% vs. 1.67%, p=0.144), though not statistically significant. Conclusion: Postoperative hypophosphatemia is common in open-heart surgery and is associated with prolonged ICU stay, MV, and increased morbidity. Early identification and management may improve patient outcomes. | ||
| Keywords | ||
| Keywords: Hypophosphatemia; Open-Heart surgery; Mechanical Ventilation; Phosphate Imbalance; Inotropic Support | ||
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