Association of some parasitic infections with autism spectrum disorder: A link to be validated | ||||
| Microbes and Infectious Diseases | ||||
| Articles in Press, Accepted Manuscript, Available Online from 14 August 2025 | ||||
| Document Type: Review Article | ||||
| DOI: 10.21608/mid.2025.406311.3040 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Sara A Abdel-Rahman1; Eman M Mostafa1; Aya I Mohamed2; Sara Maged Yousef  1; Shaimaa Elsayed Ashoush 1
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| 1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Egypt | ||||
| 2Psychiatry Department, Faculty of Medicine, Zagazig University, Egypt | ||||
| Abstract | ||||
| Background: Parasitic diseases pose a significant health challenge in developing nations, particularly among children. Considering their significant morbidity and mortality, some parasitic infections are linked to some mental disorders. Humans could be infected by different types of parasitic infections primarily classified as protozoa and helminths. The global incidence of autism spectrum disorder has been on the rise. While the precise origins of autism are still not fully understood, it is thought that a mix of genetic, environmental, and biological influences plays a role in its emergence. Environmental factors include different types of infections. This review aims to figure out the correlation between some parasitic infections and autism spectrum disorder. As this link is not yet clearly verified, we aim to find out whether some parasitic infections are a possible cause or a result of this disorder. Understanding this correlation is an optimistic key in the treatment of those patients or enhancing their condition and quality of life, reducing morbidity and mortality rates, and minimizing the financial strain on both patients and the government. | ||||
| Keywords | ||||
| Helminths; protozoa; toxoplasma; gut brain axis; ASD | ||||
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