Assessment of multi drug resistant Acinetobacter baumannii and Pseudomonas aeruginosa
Lekhwar, R., Kumar, S., Gangola, S., Shukla, R., Karmakar, R., Sharma, A. (2025). Assessment of multi drug resistant Acinetobacter baumannii and Pseudomonas aeruginosa. EKB Journal Management System, (), -. doi: 10.21608/mid.2025.395245.2911
Rajeshwari Lekhwar; Sunil Kumar; Saurabh Gangola; Ratnakar Shukla; Rachan Karmakar; Anil Kumar Sharma. "Assessment of multi drug resistant Acinetobacter baumannii and Pseudomonas aeruginosa". EKB Journal Management System, , , 2025, -. doi: 10.21608/mid.2025.395245.2911
Lekhwar, R., Kumar, S., Gangola, S., Shukla, R., Karmakar, R., Sharma, A. (2025). 'Assessment of multi drug resistant Acinetobacter baumannii and Pseudomonas aeruginosa', EKB Journal Management System, (), pp. -. doi: 10.21608/mid.2025.395245.2911
Lekhwar, R., Kumar, S., Gangola, S., Shukla, R., Karmakar, R., Sharma, A. Assessment of multi drug resistant Acinetobacter baumannii and Pseudomonas aeruginosa. EKB Journal Management System, 2025; (): -. doi: 10.21608/mid.2025.395245.2911

Assessment of multi drug resistant Acinetobacter baumannii and Pseudomonas aeruginosa

Microbes and Infectious Diseases
Articles in Press, Accepted Manuscript, Available Online from 14 August 2025  XML
Document Type: Review Article
DOI: 10.21608/mid.2025.395245.2911
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Authors
Rajeshwari Lekhwarorcid 1; Sunil Kumar email orcid 1; Saurabh Gangolaorcid 1; Ratnakar Shuklaorcid 2; Rachan Karmakarorcid 3; Anil Kumar Sharmaorcid 4
1Department of Microbiology, Graphic Era (Deemed to be University), Bell Road, Clement Town, Dehradun, Uttarakhand, India
2Department of Clinical Research Sharda School of Allied Health Sciences, Sharda University, Greater Noida, U.P., India
3Department of Environmental Sciences, Graphic Era (Deemed to be University), Bell Road, Clement Town, Dehradun, Uttarakhand, India
4Department of Biotechnology, School of Biological Sciences, Amity University Punjab, Mohali-140306, India
Abstract
Background: Acinetobacter baumannii and Pseudomonas aeruginosa are common cause of healthcare-associated infections and hospital outbreaks, predominantly in intensive care units. Prevalence of infections caused by these two pathogens and their presence in hospital, animals, and in the environmental showed alarming data on antimicrobial resistance. The aim of this review article was to expand the understanding of global health risks associated with multidrug resistant A. baumannii and P. aeruginosa. Recent literature survey was conducted using Pubmed database to discuss the multi-drug resistance of A. baumannii and P. aeruginosa. Considerable success of these two pathogens relies on their genomic plasticity, which foster rapid adaptation to stress and adverse environmental conditions. Virulence and multi-drug resistance profile of A. baumannii and P. aeruginosa make them important nosocomial pathogen in the healthcare setting especially in immunocompromised patients. Dissemination of both of these pathogens among patients and long-term contamination of the healthcare settings are encouraged by the ability to develop new antibiotic resistance, which poses a serious threat for public health worldwide. Herein, we described pathogenic characteristics, virulence factors, treatments available, antibiotic resistance, and manifestation. of A. baumannii and P. aeruginosa.
Keywords
Acinetobacter baumannii; Pseudomonas aeruginosa; Antimicrobial Resistance; Virulence factors
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