The relationship between H2FPEF and SYNTAX scores in patients with Acute Coronary Syndrome
Attia, A., Rashid, H., Helal, F., Allam, H. (2025). The relationship between H2FPEF and SYNTAX scores in patients with Acute Coronary Syndrome. EKB Journal Management System, (), -. doi: 10.21608/bmfj.2025.401744.2522
Ali I. Attia; Hesham K. Rashid; Fatma T. Helal; Hager I. Allam. "The relationship between H2FPEF and SYNTAX scores in patients with Acute Coronary Syndrome". EKB Journal Management System, , , 2025, -. doi: 10.21608/bmfj.2025.401744.2522
Attia, A., Rashid, H., Helal, F., Allam, H. (2025). 'The relationship between H2FPEF and SYNTAX scores in patients with Acute Coronary Syndrome', EKB Journal Management System, (), pp. -. doi: 10.21608/bmfj.2025.401744.2522
Attia, A., Rashid, H., Helal, F., Allam, H. The relationship between H2FPEF and SYNTAX scores in patients with Acute Coronary Syndrome. EKB Journal Management System, 2025; (): -. doi: 10.21608/bmfj.2025.401744.2522

The relationship between H2FPEF and SYNTAX scores in patients with Acute Coronary Syndrome

Benha Medical Journal
Articles in Press, Accepted Manuscript, Available Online from 16 August 2025  XML PDF (750.36 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2025.401744.2522
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Authors
Ali I. Attia1; Hesham K. Rashid2; Fatma T. Helal email 3; Hager I. Allam4
1Assistant Professor of Cardiology, Faculty of Medicine, Benha University
2Professor of Cardiology, Faculty of Medicine, Benha University
3M.B.B.Ch, Faculty of Medicine, Alazhar University
4Lecturer of Cardiology, Faculty of Medicine, Benha University
Abstract
Background: Acute coronary syndrome (ACS) encompasses unstable angina and myocardial infarctions (MI), both ST-elevation (STEMI) and non-ST-elevation (NSTEMI). This study aimed to evaluate the severity of coronary artery disease (CAD) in ACS patients by comparing the H2FPEF score with the SYNTAX score. Methods: This prospective observational study included 100 patients with ACS who underwent coronary angiography within two days of hospital admission. Based on SYNTAX score, patients were categorized into two groups: Group I (SYNTAX ≤ 22) and Group II (SYNTAX > 22). Echocardiographic and clinical data were collected and analyzed. Results: Group II patients showed significantly lower mean LVEF and TAPSE (p < 0.001) and higher E/e′ ratio and PASP (p < 0.05). Patients with major adverse cardiovascular and cerebrovascular events (MACCE) had notably higher mean H2FPEF scores than those without events. A strong correlation was found between higher H2FPEF and SYNTAX scores, indicating that H2FPEF can serve as a predictive marker for CAD severity and short-term outcomes. Conclusion: The H2FPEF score is a simple and effective tool for assessing CAD severity and short-term prognosis in ACS patients. Scores ≥2 are significantly associated with higher SYNTAX scores and increased risk of MACCE at 30-day follow-up, suggesting its utility in early risk stratification.
Keywords
H2FPEF; SYNTAX scores; Acute Coronary Syndrome
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