Role of MRI in Assessment of the Response Post High-Intensity Focused Ultrasound (HIFU) Treatment in Uterine Fibroids | ||||
| Ain Shams Medical Journal | ||||
| Volume 76, Issue 2, June 2025, Page 398-407 PDF (619.41 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/asmj.2025.361009.1393 | ||||
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| Authors | ||||
Michael Ezzat Narouz   1; Eman Ahmed Geneidi2; Mohammed Mohsen Tolba Fawzi3; Manar Maamoun Ashour 4
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| 1Ain Shams university | ||||
| 2Department of Diagnostic & Intervention Radiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. | ||||
| 3Diagnostic and Intervention Radiology department, National Hepatology and Tropical Medicine Research Institute. | ||||
| 4Department of Radio-diagnosis, Faculty of Medicine, Ain Shams University | ||||
| Abstract | ||||
| Background: Fibroids are the most common benign uterine tumors in women of child-bearing period. They cause an array of symptoms as dysmenorrhea, menorrhagia, menometrorrhagia, and even discomfort in the lower abdomen and infertility. Sometimes, these fibroids exert pressure on neighboring organs, leading to disruptions in urination and defecation. Aim of the Work: To evaluate the role of MRI in assessment of uterine fibroids response post HIFU treatment Patients and Methods: In this prospective study, thirty adult females with uterine fibroid diagnosed by contrast-enhanced MRI underwent HIFU ablation therapy. The clinical and laboratory outcomes were assessed in correlation with the MRI findings as regards the non-perfused (NPV) percent and volume. Results: The menstruation and pain score were notably reduced. There was substantial reduction in fibroid volume post- treatment. Reduction in NPV correlated strongly with symptom improvement. The NPV measurement was central to evaluating the procedure's success. Conclusion: HIFU is a non-invasive, uterus-preserving treatment. The NPV can be used as a crucial metric for assessing treatment outcomes and guiding clinical decisions and hence, serving as a pivotal marker of treatment success. | ||||
| Keywords | ||||
| Assessment of the response treatment; High-Intensity Focused Ultrasound (HIFU); MRI; non-perfused volume (NPV); uterine fibroids | ||||
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