Antibacterial activity of nanosilver against Escherichia coli and Pseudomonas aeruginosa | ||||
| Mansoura Journal of Biology | ||||
| Volume 62, Issue 1, March 2023, Page 35-44 PDF (1.19 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjb.2023.447847 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Nada H. Ghazala* 1; Ashraf Elsayed1; Attiya Mohamedin1; Mohamed O. Abdel-Monem2 | ||||
| 1Botany Department, Faculty of Science, Mansoura University, Egypt | ||||
| 2Botany Department, Faculty of Science, Banha University, Egypt | ||||
| Abstract | ||||
| Multidrug resistance bacteria are a major health concern so new strategies for controlling bacterial activity such as nanoparticles are urgently needed. Fusarium oxysporum-based biological approaches for nanoparticle synthesis have been proposed as promisingly green processes. By using UV-visible spectroscopy, which demonstrated a maximum absorption at 434 nm, biosynthesized silver nanoparticles (AgNPs) were characterized. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) techniques showed that monodispersed spherical shapes with mean diameters of 6-50 nm were formed and zeta potential analysis displayed (-16.7) mV with a single. The MIC of biosynthesized AgNPs for each bacteria (Escherichia coli and Pseudomonas aeruginosa) was determined. The concentration of 10 µg/ml of nano-silver completely inhibited the growth of all tested bacteria. The antibacterial effect of AgNPs on E. coli and P. aeruginosa showed a great potential effect of AgNPs than Ceftriaxone, while an increase of the inhibition zone diameter in the case of AgNPs antibiotic mixture had been investigated. In conclusion, future therapeutic mechanism for multi-drug resistant pathogenic bacterial have a lot of potential for using silver nanoparticles as an efficient antibacterial agent. | ||||
| Keywords | ||||
| MDR bacteria; F. oxysporum; Silver nanoparticles; Antibacterial activity | ||||
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