Intradialytic Hypotension in Hemodialysis Patients and Its Relation to Duration of Hemodialysis | ||||
Journal of Current Medical Research and Practice | ||||
Volume 10, Issue 3, July 2025, Page 1-8 PDF (372.15 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/jcmrp.2024.268891.1010 | ||||
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Authors | ||||
Mahmoud Fahmy ![]() | ||||
1Nephrology Unit, Assiut Health Insurance Hospital, Assiut, Egypt. | ||||
2Department of Internal Medicine- Faculty of Medicine, Assiut University, Assiut, Egypt. | ||||
Abstract | ||||
Abstract: Background and Aim: Intradialytic hypotension (IDH) is known to be one of the most frequent complications of hemodialysis. This study aims to assess IDH frequency in chronic kidney disease (CKD) patients on chronic hemodialysis. Patients and Methods: A cross-sectional study was conducted on hemodialyzed end-stage kidney disease patients (ESRD, 94 patients) on regular hemodialysis. All patients were treated with high-permeability membranes. We excluded patients with advanced heart failure according to the criteria of the European Society of Cardiology and clinically unstable patients who required hospital admission. So, our study included 90 patients after the exclusion of 4 patients due to advanced heart failure and patients needing hospital admission. For all patients, a full history was taken before the dialysis session. Blood pressure (BP) was measured with a mercury sphygmomanometer before, after, and every 60 min during the hemodialysis session (a total of 5 measurements) for 10 consecutive dialysis sessions. Results: Only 25 patients (27.8 %) had IDH. Patients suffering from IDH had a longer duration of dialysis in comparison to those patients without IDH (6.84 ± 1.17 vs. 3.75 ± 1.13 (years)), with lower serum albumin (3.5 ± 0.15 vs. 4.21 ± 0.12 (g/dl)) and significantly higher glycosylated haemoglobin (8.09 ± 2.22 vs. 5.45 ± 1.90 (%)). Patients suffering from autonomic neuropathy were more liable to IDH based on heart rate response to deep breathing test (76% vs. 27.75%) and based on blood pressure response to standing (68% vs. 23.1%) in comparison to those without IDH. Conclusion: Based on the current study, predictors of IDH were female sex, long duration of dialysis, low serum albumin, high glycosylated haemoglobin, and autonomic neuropathy based on heart rate response test and BP response test. | ||||
Keywords | ||||
Keywords: Blood pressure; heart rate; autonomic neuropathy | ||||
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