Neurologic Deterioration After Intravenous Thrombolysis Among Stroke Patients in Assiut University Hospitals | ||||
| Journal of Current Medical Research and Practice | ||||
| Volume 10, Issue 3, July 2025, Page 9-16 PDF (193.34 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jcmrp.2024.269720.1011 | ||||
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| Authors | ||||
Mohamed Abd-elrahman Ahmed; Ahmed Nasreldein Mohamed; Osama Ibrahim Aboelfath 
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| Neuropsychiatry Department, Faculty of Medicine, Assiut University, Egypt. | ||||
| Abstract | ||||
| Abstract: Background: Cerebrovascular Disease is categorized in the ICD-11 as Acute focal neurological impairment due to focal infarction at one or more locations in the brain or retina, also known as a stroke. The risk of early neurological decline (END) after recanalization therapy is a major concern. Aim and Objectives: To investigate the prevalence of neurological deterioration in individuals with acute ischemic stroke who have received thrombolytic therapy. Subjects and Methods: This prospective study was conducted at the Neurology Department Stroke Unit, Assiut University Hospitals, Assiut, Egypt, and included all acute ischemic stroke individuals stated in the duration from 1/1/2021 to 31/12/2021 Result: The survival rate was (93%), 69% of patients showed significant improvement in NIHSS and mRS at 24h, and progressive improvement within 7 days of follow-up, 27% showed no difference in NIHSS or mRS at 24h, 3 days, 7 days of follow-up, and 4% showed deterioration at follow-up points without significant changes in NIHSS & mRS. Also, 68% showed a significant reduction in mRS from baseline to one month of follow-up. Conclusion: Early neurological deterioration was prevalent among cases with acute ischemic stroke after successful recanalization, with an incidence rate of 10.1%. | ||||
| Keywords | ||||
| Keywords: Early Neurological Deterioration; Recanalization Treatment; Acute Ischemic Stroke | ||||
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