Impact of Chronic Migraine Remission on Headache-related Disability | ||||
| Journal of Current Medical Research and Practice | ||||
| Volume 10, Issue 3, July 2025, Page 27-36 PDF (324.66 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jcmrp.2024.279177.1038 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Tarek A. Rageh; Mostafa O. Abdelazez  ; Hassan M Farweez
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| Neurology Department, Faculty of Medicine, Assiut University, Assiut, Egypt. | ||||
| Abstract | ||||
| Abstract: Background: Chronic migraine (CM) is a severe neurological condition that significantly impairs personal and socioeconomic outcomes. The existing research aimed to evaluate the effect of chronic migraine remission on headache-related disability and assess the rate of chronic migraine remission. Patients and Methods: This is a prospective study, which included all diagnosed CM patients according to the diagnostic criteria of chronic migraine of ICHD3, who attended the outpatient Headache Clinic, Neuropsychiatry Department at Assiut University Hospital in the period from the beginning of 2021 up to the end of 2022. Headache Sheets and clinical rating scales related to headache severity and frequency were used to assess headache patterns and the impact of headache severity among CM patients. All were followed up at 24 months. Results: Out of 300 CM patients eligible for the study and complete follow-up, 27.3 % remitted CM, while 39.0% and 33.7 % had persistent CM and transitional CM, respectively. By using Migraine Disability Assessment Test (MIDAS), we found that 50.2% had moderate to severe disability. Based on Migraine Specific Quality of Life Questionnaire (MSQ) score, cases with remitting headaches at baseline had a significantly higher mean score, 59.4 ± 9.9 than those with persistent headaches 43.7 ± 10, P < 0.001; the same was observed after 2 years of follow-up; 67.9 ± 7 versus 40 ± 10.4, P < 0.001 respectively. Conclusion: These results confirm that cases with persistent chronic migraine have persistently increased disability compared with cases with remitting chronic migraine. | ||||
| Keywords | ||||
| Keywords: Chronic migraine (CM); remission; headache-related disability | ||||
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