Correlation Between Inflammatory Markers and CBC indices (WBCs and platelets) in Severely Malnourished Children | ||||
| Journal of Current Medical Research and Practice | ||||
| Volume 10, Issue 3, July 2025, Page 153-160 PDF (295.63 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jcmrp.2025.340910.1165 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Amir Mohammed Abo El Gheet; Emad El Deen Mahmoud Hammad; Meret Michael Fahmy  ; Khalaf Abdelaal Sayed
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| Pediatric Department, Faculty of Medicine, Assiut University, Egypt. | ||||
| Abstract | ||||
| Abstract: Background: Malnutrition is a prevalent worldwide health problem caused by a lack of or excess of essential nutrients. This condition can be identified through a clinical examination or by measuring biochemical or anthropometric factors. Aim and Objectives: To assess the efficacy of quantitative C-reactive protein as a prognostic indicator for severe infections in kids with acute severe malnutrition and to establish a correlation among inflammatory markers and complete blood count indices, particularly platelets and WBCs, in these kids. Patients and Methods: This prospective analytic research was performed on sixty cases separated into two groups: The 1st group with systemic onset of infection (30 patients) and the 2nd group without systemic onset of infection (30 patients) at Assiut University Children's Hospital in a period of one year from January 1st, 2022, up to December 31st, 2022. Results: There was highly statistically significant variance (p= <0.001) among both groups regarding WBC. Both groups had statistically insignificant variation according to platelet count (PLT) and aggregation index. CRP demonstrated a significant positive association with WBCs and PLT, while CRP demonstrated a significant negative association with HCT. ESR showed a significant positive association with WBCs and PLT, while ESR showed a significant negative correlation with HCT. Conclusion: There is a positive correlation between inflammatory markers, including ESR, CRP, and serum ferritin, and CBC indices, including WBC and platelets, while for HCT, there is a negative correlation between it and the inflammatory markers in severely malnourished children. | ||||
| Keywords | ||||
| Keywords: Malnutrition; CBC indices; inflammatory markers | ||||
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