The Impact of Intravenous Glucose Administration on Maintenance of Body Temperature during Total Knee Replacement under Spinal Anesthesia in Geriatric Patients: A Randomized Controlled Trial | ||
| International Journal of Medical Arts | ||
| Articles in Press, Accepted Manuscript, Available Online from 22 August 2025 PDF (954.44 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ijma.2025.407639.2228 | ||
| Authors | ||
| Tarek Habeeb Ramadan* 1; Waleed M R Elsarraf1; Mohanad Abdulqader Atta2; Mohamed Aly Eloraby1 | ||
| 1Department of anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Mansoura University, Mansoura , Egypt | ||
| 2Consultant Anesthetist, Dubai Health Authority, Dubai, UAE. | ||
| Abstract | ||
| Background: Total knee replacement [TKR], more common in the elderly, can cause inadvertent perioperative hypothermia, which can be prevented. Preoperative intravenous [IV] glucose may minimize heat loss by increasing metabolism and heat generation. The aim of the work: This study examined how preoperative IV 10% glucose affected body temperature in elderly TKR patients under spinal anesthesia [SA]. Patients and Methods: This randomized controlled trial involved 78 ASA I-II elderly patients scheduled for elective TKR under SA. Eligible patients were randomly allocated into two equal groups: group A received a 10% glucose infusion, while group B received 0.9% normal saline [NS], administered 6 hours before surgery. The occurrence of hypothermia was the primary outcome. Results: At the end of surgery, group B exhibited a notable significant lower value of core temperature [p<0.001] with a non-significant alteration in surface temperature [p=0.087] than group A. Group B experienced more adverse effects compared to group A with statistically significant differences, particularly hypothermia [p= 0.040] and shivering [p=0.007]. Conclusion: Elderly individuals undergoing total knee replacement under spinal anesthesia may benefit from a preoperative intravenous infusion of 10% glucose to help control body temperature and avoiding shivering. | ||
| Keywords | ||
| Glucose; Temperature; Hypothermia; Total Knee Replacement; Geriatric | ||
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