Enhancing Nutritional Quality and Antidiabetic Effects of Pan Bread Fortified with Germinated Red Radish Seed Powder | ||||
Egyptian Journal of Chemistry | ||||
Articles in Press, Accepted Manuscript, Available Online from 23 August 2025 | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejchem.2025.400429.12006 | ||||
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Authors | ||||
Ekram H. Barakat1; Raghda A. Abu Ahmed2; gamal saad elhadidy ![]() ![]() | ||||
1Home Economics Department, Faculty of Specific Education, Kafrelsheikh University, Kafrelsheikh, Egypt | ||||
2Department of Food Sciences and Technology, Faculty of Agriculture, Damanhur University, Egypt | ||||
3kafrelshiekh | ||||
4Nutrition and Food Science Dept., Faculty of Home Economics Menoufia University, Shebin El-Kom, Egypt | ||||
Abstract | ||||
This study aimed to investigate the nutritional and therapeutic potential of germinated red radish seed powder (GRRSP) as a functional ingredient in pan bread and its effects on biochemical parameters in diabetic rats. Proximate analysis revealed that GRRSP contained significantly higher levels of protein (35.20%), fiber (19.50%), and ash (10.80%) compared to wheat flour, along with lower carbohydrate and fat content. GRRSP was also rich in essential minerals such as potassium (1020 mg/100g), calcium, magnesium, phosphorus, and iron, and exhibited elevated levels of bioactive compounds, including total phenolics (9.59 mg GAE/g), flavonoids (0.85 mg QE/g), and antioxidant activity (91.30%). Substituting wheat flour with GRRSP (2.5–10%) in pan bread formulations improved the nutritional profile, especially in protein, fiber, and mineral content. However, higher substi-tution levels adversely affected loaf volume, crumb texture, and sensory scores, with blends containing up to 5% GRRSP main-taining acceptable sensory quality. In vivo, diabetic rats fed diets containing GRRSP showed dose-dependent improvements in blood glucose levels, lipid profiles, and liver enzyme activities over a six-week period. At 10% GRRSP inclusion, blood glucose levels decreased by 45%, while HDL increased and LDL, total cholesterol, and triglycerides significantly decreased. Liver en-zymes (ALT, AST, ALP) also declined toward normal values, suggesting hepatoprotective effects. These findings demonstrate that GRRSP can serve as a functional food ingredient with substantial nutritional enhancements and antidiabetic effects, support-ing its potential use in therapeutic diet formulations and functional bakery products. | ||||
Keywords | ||||
Germinated red radish seeds; functional bread; diabetes; antioxidant activity; lipid profile; liver enzymes; bioactive compounds | ||||
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