Tripolyphosphate-Driven Synthesis of Ag3PO4-Decorated Chitosan Nanoparticles for Enhanced Antimicrobial Activity
Alafifya, A., Dawwam, G., Abdel Salam, S., Mohamed, M., Al-Shemy, M. (2025). Tripolyphosphate-Driven Synthesis of Ag3PO4-Decorated Chitosan Nanoparticles for Enhanced Antimicrobial Activity. EKB Journal Management System, (), -. doi: 10.21608/ejchem.2025.400788.11998
Asmaa N. Alafifya; Ghada Dawwam; Soheir Abdel Salam; Manal Selim Mohamed; Mona Tawfik Al-Shemy. "Tripolyphosphate-Driven Synthesis of Ag3PO4-Decorated Chitosan Nanoparticles for Enhanced Antimicrobial Activity". EKB Journal Management System, , , 2025, -. doi: 10.21608/ejchem.2025.400788.11998
Alafifya, A., Dawwam, G., Abdel Salam, S., Mohamed, M., Al-Shemy, M. (2025). 'Tripolyphosphate-Driven Synthesis of Ag3PO4-Decorated Chitosan Nanoparticles for Enhanced Antimicrobial Activity', EKB Journal Management System, (), pp. -. doi: 10.21608/ejchem.2025.400788.11998
Alafifya, A., Dawwam, G., Abdel Salam, S., Mohamed, M., Al-Shemy, M. Tripolyphosphate-Driven Synthesis of Ag3PO4-Decorated Chitosan Nanoparticles for Enhanced Antimicrobial Activity. EKB Journal Management System, 2025; (): -. doi: 10.21608/ejchem.2025.400788.11998

Tripolyphosphate-Driven Synthesis of Ag3PO4-Decorated Chitosan Nanoparticles for Enhanced Antimicrobial Activity

Egyptian Journal of Chemistry
Articles in Press, Accepted Manuscript, Available Online from 24 August 2025  XML
Document Type: Original Article
DOI: 10.21608/ejchem.2025.400788.11998
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Authors
Asmaa N. Alafifya1; Ghada Dawwamorcid 2; Soheir Abdel Salam1; Manal Selim Mohamedorcid 3; Mona Tawfik Al-Shemy email orcid 4
1Botany and Microbiology Department, Faculty of Science, Benha University, Benha, 13518, Egypt.
2Botany and Microbiology Department, Faculty of Science, Benha University, Benha, 13518, Egypt
3Microbial Biotechnology Department, Biotechnology Research Institute, National Research Centre, Cairo, Egypt
4National research centre Cellulose & Paper Department
Abstract
Overuse of conventional antibiotics has fueled the rise of drug-resistant pathogens, creating an urgent need for novel antimicrobial platforms. In this study, we developed a novel, green, one-pot tripolyphosphate-driven method to fabricate chitosan (CS) nanoparticles from black soldier fly (Hermetia illucens) puparia and simultaneously deposit crystalline Ag3PO4 (AgP) domains to yield a CS@AgP bionanocomposite. Comprehensive FTIR, XRD, and UV–Vis DRS analyses confirmed successful Ag3PO4 incorporation and a narrowed direct band gap of 1.46 eV. Agar-diffusion assays against Gram-positive (L. monocytogenes ATCC 7646, S. aureus ATCC 6538), Gram-negative (E. coli ATCC 25922, Salmonella sp. ATCC 14028), and fungal (C. albicans ATCC 10231) strains demonstrated dose-dependent inhibition zones up to 30 mm at 25 mg/mL. This dual-function nanocomposite combines sustainable, single-step production with broad visible-light absorption and potent antimicrobial efficacy, offering a versatile platform for antimicrobial coatings and photocatalysis.
Keywords
Bio-nanocomposite; Chitosan nanoparticles (CSNPs); Green synthesis; Pathogenic microbes; Soldier fly Puparia; Silver phosphate (Ag₃PO₄) nanoparticles
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