Role of TIRADS and Bethesda Scoring Systems in Management of Thyroid Nodules | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 181, Volume 100, Issue 1, July 2025, Page 3813-3820 PDF (663.58 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejhm.2025.449119 | ||||
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Abstract | ||||
Background: Fine-needle aspiration (FNA) is the first-line diagnostic procedure, with the Bethesda System used to classify cytology findings into six categories based on malignancy risk. Despite some diagnostic variability, this system enhances diagnostic accuracy and minimizes unnecessary surgeries. Objective: This study aimed to measure the correlation between the thyroid imaging reporting and data systems (TIRADS) and Bethesda scoring systems and the final histopathology, whether benign or malignant, in thyroid nodules (TNs). Patients and Methods: This cross-sectional observational study was conducted on 30 patients with single or multiple thyroid nodules measuring more than 1cm. All patients underwent FNA cytology from suspicious nodules. Patients with thyroid nodules that are smaller than 1cm, history of thyroid surgery and history of radiotherapy were excluded from the study. Results: TIRAD can significantly predicted histopathology (P = 0.018, AUC = 0.683) at cut-off ≤ 3 with 90.00 % sensitivity, 45.00 % specificity, 71.1 % PPV and 75.0% NPV. Bethesda system significantly predicted histopathology (P = 0.032, AUC = 0.659) at cut-off ≤ 2 with 73.33 % sensitivity, 55.00% specificity, 71.0% PPV and 57.9% NPV. Conclusions: Both TIRAD and the Bethesda system are significant predictors of the histopathology of thyroid nodules, with superiority of TIRAD in sensitivity (90%) compared to the Bethesda system (73.33 %). | ||||
Keywords | ||||
TIRADS; Bethesda Scoring System; Thyroid Nodules; FNA | ||||
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