Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography
Abdelghany, A., Elnahrawy, O., Zaky, K., Zidan, M. (2025). Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography. EKB Journal Management System, 2025(3), 208-213. doi: https://doi.org/10.21608/aimj.2025.446489
Ahmed Anwar Abdelghany; Osama Mohy Elden Elnahrawy; Khaled Abdelsalam Zaky; Mohammed Fathi Abdelaziz Zidan. "Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography". EKB Journal Management System, 2025, 3, 2025, 208-213. doi: https://doi.org/10.21608/aimj.2025.446489
Abdelghany, A., Elnahrawy, O., Zaky, K., Zidan, M. (2025). 'Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography', EKB Journal Management System, 2025(3), pp. 208-213. doi: https://doi.org/10.21608/aimj.2025.446489
Abdelghany, A., Elnahrawy, O., Zaky, K., Zidan, M. Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography. EKB Journal Management System, 2025; 2025(3): 208-213. doi: https://doi.org/10.21608/aimj.2025.446489

Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography

Al-Azhar International Medical Journal
Volume 2025, Issue 3, March 2025, Page 208-213  XML PDF (473.18 K)
Document Type: Original Article
DOI: https://doi.org/10.21608/aimj.2025.446489
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Authors
Ahmed Anwar Abdelghany1; Osama Mohy Elden Elnahrawy1; Khaled Abdelsalam Zaky2; Mohammed Fathi Abdelaziz Zidan email 3
1Professor of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
2Assistant Professor of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
3MBBCh, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Abstract
Background: Worldwide, smoking causes premature death among the elderly and impacts nearly every organ in the body. Additionally, it significantly increases the likelihood of developing cognitive decline, Alzheimer's disease, and dementia.
Aim and objectives: To evaluate the effect of smoking on macular perfusion using optical coherence tomography angiography (OCTA).
Subjects and methods: This case-control study was conducted on 96 eyes of patients at the ophthalmology outpatient clinic, Suez Canal University Hospital, Ismailia, Egypt, from January 2023 to January 2024.
Results: When comparing smokers' eyes to those of healthy people who do not smoke, we see that the former have a larger FAZ and smaller foveal VD of the superior ciliary plane and inferior ciliary plane, respectively. The control group had a mean whole superficial layer density of 49.51±2.96, while the smoker's group had 47.30±3.29, with a statistically significant P-value<0.001. With a statistically significant P-value<0.001, the control group had a mean entire deep layer density of 51.15±5.29 while the smoker's group had 45.69±4.62. The control group had a mean FAZ area (mm2) of 0.24±0.08 while the smoker's group had a mean of 0.32±0.09, with a statistically significant P-value<0.001.
Conclusion: Smoking has obvious consequences on the eyes, particularly on the macular perfusion. A notable decline in VD, particularly in deep layer density, and an expansion of FAZ area were noted.
 
Keywords
Smoking; Macular perfusion; Optical coherence tomography angiography
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