Estimation of some markers in renal failure patients with toxoplasmosis Infection | ||||
Microbes and Infectious Diseases | ||||
Articles in Press, Accepted Manuscript, Available Online from 25 August 2025 | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mid.2025.380874.2748 | ||||
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Authors | ||||
Nawras A. Esmaeel ![]() | ||||
Al-Furat Al-Awsat Technical University, Karbala Technical Institute, Iraq | ||||
Abstract | ||||
Background This study explores the influence of Toxoplasma gondii infection on renal function among chronic kidney disease (CKD) patients. Methods: A total of sixty infected patients and twenty healthy controls were included in the analysis. Serological tests were performed to detect T. gondii IgG and IgM antibodies, alongside the evaluation of biochemical markers such as creatinine, urea, and electrolytes. Results: The revealed significantly elevated levels of creatinine and urea in infected CKD patients, indicating severe impairment of kidney function. Disturbances in calcium and phosphate metabolism were also observed, highlighting the systemic effects of T. gondii. Interestingly, iron levels were reduced, correlating with risks of anemia, while sodium and potassium levels remained stable. underscore the parasite's role in exacerbating renal dysfunction and associated complications. Conclusion: Monitoring T. gondii exposure and biochemical markers in CKD patients is crucial to improving management strategies and reducing morbidity risks. | ||||
Keywords | ||||
T. gondii; CKD; hemodialysis | ||||
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