Preparation and characterization of chitosan/PVA composite reinforced with natural hydroxyapatite nanoparticles | ||
| Egyptian Journal of Chemistry | ||
| Articles in Press, Accepted Manuscript, Available Online from 26 August 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2025.377868.11702 | ||
| Authors | ||
| Jacqueline N. Omar1; Amr M. Abdelghany2; Dalia M. Ayaad1; Magdy Y. Abdelaal1 | ||
| 1Chemistry Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt. | ||
| 2Spectroscopy Department, Physics Research Institute, National Research Center, 33 El-Behouth St., Dokki, 12311, Giza, Egypt. | ||
| Abstract | ||
| This study investigates the synthesis and characterization of novel biocomposite materials based on chitosan, polyvinyl alcohol (PVA), and hydroxyapatite (HA) derived from bovine bone, offering a sustainable and cost-effective approach for biomedical applications. Thin films were prepared using a simple casting technique, incorporating HA filler up to 32% w/w, and their structural, optical, and surface properties were extensively analyzed. X-ray diffraction (XRD) confirmed the crystalline nature of the synthesized HA, matching JCPDS no. 09-0432, while Fourier-transform infrared spectroscopy (FTIR) verified the preservation of key functional groups and indicated potential complexation between components. UV-Visible spectroscopy revealed shifts in optical properties, corroborated by density functional theory (DFT) calculations, suggesting enhanced material performance. Scanning electron microscopy SEM analysis demonstrated that HA nanoparticle incorporation induced surface roughness and grain formation due to heterogeneous nucleation of HA crystals and interfacial interactions with the polymer matrix, enhancing potential bioactivity for bone tissue engineering. The findings highlight the potential of these composites as promising candidates for biomedical applications, combining the biocompatibility of chitosan and PVA with the bioactive properties of natural HA. This work advances the understanding of polymer-ceramic composites and their tunability for specific medical uses. | ||
| Keywords | ||
| HA; biocomposite; PVA/Chitosan; DFT; Swelling | ||
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