Detection of the prevalence and risk factors of acute H. pylori infection among patients with gastroenteritis | ||||
| Microbes and Infectious Diseases | ||||
| Articles in Press, Accepted Manuscript, Available Online from 26 August 2025 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mid.2025.401411.2998 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Salah Hameed Yaseen  ; Mahdi Hussain Alammar
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| Department of Biology, College of Science, University of Kufa, Najaf, Iraq | ||||
| Abstract | ||||
| Background and Objective :This study investigates the demographic and immunological characteristics of acute Helicobacter pylori infection among Iraqi patients presenting with gastrointestinal symptoms. This study design to explore the distribution of acute H. pylori infection among Iraqi patients according age and sex, to show the prevalence the H.pylori among patients with gastric ulcer. Methods: A total of 100 participants were included, divided equally into patient and control groups based on stool antigen testing. The age distribution revealed a higher proportion of patients under 20 years (28%) compared to controls (20%), while the 40–59 age group had more controls (28%) than patients (22%). Females were slightly more represented in both groups. Results: Gender-specific age analysis showed a broader and more balanced distribution among females, while males were more concentrated in the 30–39 age group. However, no statistically significant association was found between age group and infection status (p = 0.6293), suggesting a uniform distribution of H. pylori across age categories. Analysis of ABO blood groups indicated that A+, B+, and O+ were more common among positive cases, though this association was not statistically significant (p = 0.0940). Evaluation of humoral immune responses showed no significant differences in serum IgA and IgM levels between infected and control groups (p > 0.05). Conclusions: These findings indicate that the serum IgA and IgM markers and age, sex, ABO blood group, do not significantly impact on the likelihood of acute H. pylori infection among patients with Gastroenteritis .The gender is not associated with infection risk in this sample, while the female group had a higher number of positive cases, the difference between genders was not statistically significant, as confirmed by Fisher’s exact test (p = 0.6753). | ||||
| Keywords | ||||
| Acute H. pylori; Age; Gender; Stool Antigen.IgM.IgA | ||||
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