Role of Long non-coding RNA Gene Expression in Breast Cancer | ||
| Egyptian Reviews for Medical and Health Sciences | ||
| Volume 6, Issue 1, September 2025, Pages 66-76 PDF (318.74 K) | ||
| Document Type: Review article | ||
| DOI: 10.21608/ermhs.2025.416624.1068 | ||
| Authors | ||
| Dalia Abdelnasser Awad Mohammed* 1; Ahmed Mostafa Elzawawy2; Hoda Yousry Abdullah3; Mahinour Mohamed Atef4; Lubna Omar El-Farouk Abdel Salam5; Hanan Ezzat Shafik6 | ||
| 1MBBCh, M.S.C, Assistant-Lecturer of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Suez Canal University. | ||
| 2Professor of Clinical Oncology, Faculty of Medicine, Suez Canal University. | ||
| 3Assistant Professor of Medical Genetics, Faculty of Medicine, Suez Canal University. | ||
| 4Lecturer of Clinical Oncology, Faculty of Medicine, Suez Canal University. | ||
| 5Professor Of Pathology, Faculty Of Medicine, Cairo University. | ||
| 6Professor of Medical Oncology NCI Cairo university. | ||
| Abstract | ||
| One of the most prevalent illnesses in women, breast cancer is thought to be a complex and diverse condition that continues to be a significant public health issue. Long non-coding RNAs have drawn a lot of interest lately because of the advancement of next-generation sequencing methods. Long non-coding RNAs have been shown in several studies to play significant roles in the formation of tumors. Recent studies have shown that a variety of long non-coding RNAs express aberrantly in malignancies, including breast cancer, despite the fact that the biological role and molecular processes of these RNAs are still unknown. With an emphasis on the many molecular functions of regulatory long non-coding RNAs that control cell proliferation, invasion, metastasis, and apoptosis, we have included the most recent research on long non-coding RNAs in breast cancer here. One of the most prevalent illnesses in women, breast cancer is thought to be a complex and diverse condition that continues to be a significant public health issue. Long non-coding RNAs have drawn a lot of interest lately because of the advancement of next-generation sequencing methods. Long non-coding RNAs have been shown in several studies to play significant roles in the formation of tumors. Recent studies have shown that a variety of long non-coding RNAs express aberrantly in malignancies, including breast cancer, despite the fact that the biological role and molecular processes of these RNAs are still unknown. | ||
| Keywords | ||
| Gene Expression; Breast Cancer; Long non-coding RNA | ||
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