Neutrophil to Lymphocyte Ratio as a predictor of myocardial contractility post-ST Segment Elevation Myocardial Infarction in young and middle-aged patients | ||||
Minia Journal of Medical Research | ||||
Articles in Press, Accepted Manuscript, Available Online from 01 September 2025 | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjmr.2025.404322.2032 | ||||
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Authors | ||||
Sarah Eid Ibraheem ![]() | ||||
1Cardiology department, Faculty of Medicine, Minia University, El-Minya | ||||
2cardiology ,faculty of medicine , minia university . Minia | ||||
3Cardiology department, Faculty of Medicine, Minia University | ||||
Abstract | ||||
Background:NLR is known to be more elevated in patient with worse LV systolic function.Aim:detect relation between NLR and GLS in young and middle-aged STEMI patients. Methods:We investigated NLR & GLS in 56 patients during CCU STEMI admission and follow up NLR & GLS were done month later. Percentage of change of follow-up NLR in relation to the baseline admission NLR is calculated in each patient. Results: Baseline NLR shows moderate positive correlation with admission GLS (p<0.001 & r= 0.593) and fair positive correlation with follow-up GLS (p<0.001 & r= 0.481). Follow-up NLR shows moderate positive correlation with follow-up GLS (p<0.001 & r= 0.613). Percentage of NLR decline was related to GLS improvement state with means being about 56.52% in the group whose GLS improved after 1 month and only about 10.16% in the group whose GLS not improved. From. NLR was significantly higher in GLS>-13.8% group 6.06 (5.43±3.45) compared to (2.39±1.05) in GLS≤-13.8% group, p<0.001. By ROC curve,the cut-off value of NLR was 2.547. Multivariate analysis showed patients with higher NLR >2.547 are more probable to develop GLS>-13.8% Conclusion:STEMI patients with high NLR have a greater chance to have worse LV systolic function at MI presentation and after one month | ||||
Keywords | ||||
STEMI; NLR; LV GLS | ||||
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