Evaluation of Ascitic Calprotectin Level in Diagnosis of Spontaneous Bacterial Peritonitis in HCV Egyptian Patients with Liver Cirrhosis and Its Outcome
Bahnacy, A., hussieny, B., Gadallah, A. (2025). Evaluation of Ascitic Calprotectin Level in Diagnosis of Spontaneous Bacterial Peritonitis in HCV Egyptian Patients with Liver Cirrhosis and Its Outcome. EKB Journal Management System, 100(1), 3942-3949. doi: 10.21608/ejhm.2025.411867.1815
Abd-allah Bahnacy; basma hussieny; Abdel-Naser Abdel-Atty Gadallah. "Evaluation of Ascitic Calprotectin Level in Diagnosis of Spontaneous Bacterial Peritonitis in HCV Egyptian Patients with Liver Cirrhosis and Its Outcome". EKB Journal Management System, 100, 1, 2025, 3942-3949. doi: 10.21608/ejhm.2025.411867.1815
Bahnacy, A., hussieny, B., Gadallah, A. (2025). 'Evaluation of Ascitic Calprotectin Level in Diagnosis of Spontaneous Bacterial Peritonitis in HCV Egyptian Patients with Liver Cirrhosis and Its Outcome', EKB Journal Management System, 100(1), pp. 3942-3949. doi: 10.21608/ejhm.2025.411867.1815
Bahnacy, A., hussieny, B., Gadallah, A. Evaluation of Ascitic Calprotectin Level in Diagnosis of Spontaneous Bacterial Peritonitis in HCV Egyptian Patients with Liver Cirrhosis and Its Outcome. EKB Journal Management System, 2025; 100(1): 3942-3949. doi: 10.21608/ejhm.2025.411867.1815

Evaluation of Ascitic Calprotectin Level in Diagnosis of Spontaneous Bacterial Peritonitis in HCV Egyptian Patients with Liver Cirrhosis and Its Outcome

The Egyptian Journal of Hospital Medicine
Volume 100, Issue 1, July 2025, Page 3942-3949  XML PDF (642.78 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2025.411867.1815
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Authors
Abd-allah Bahnacy1; basma hussieny email 2; Abdel-Naser Abdel-Atty Gadallah3
1Gastroenterology and Hepatology department, Faculty of Medicine, Menoufia University
21Gastroenterology and Hepatology department, Faculty of Medicine, Menoufia University.
3Internal Medicine, Gastroenterology, Hepatology & Endoscopy department, Faculty of Medicine - Menoufia University, Shebin Elkom, Menoufia, Egypt
Abstract
Background: A dangerous side effect of cirrhosis, particularly in people with hepatitis C, is spontaneous bacterial peritonitis (SBP). A diagnosis made early is essential for better results. As a potential diagnostic marker for SBP, ascetic calprotectin has demonstrated promise.
Objective: This study aimed to assess ascetic calprotectin levels in the diagnosis of SBP and its consequences in liver cirrhosis patients with HCV in Egypt.
Methods: This was a case-control hospital-based study on 120 cirrhotic Egyptian patients with ascites with different demographic data presented to the Hepatology Department of Shebin El-Kom Teaching Hospital and the Internal Medicine Department of Menoufia University Hospitals during the period from March 2023 till June 2024.
Results: Logistic regression analysis indicated ascetic calprotectin, ascetic TLC, urea, GFR, albumin and respiratory rate were the most significant independent factors associated with the mortality among the studied patients (p<0.05). While, other variables did not show significant relation with mortality rate (p>0.05).
Conclusion: Logistic regression analysis indicated ascetic calprotectin, ascetic TLC, urea, GFR, albumin and respiratory rate were the most significant independent factors associated with the mortality among the studied patients (p<0.05). While other variables did not significant relation with mortality rate (p>0.05).
 
Keywords
Ascetic calprotectin; Bacterial peritonitis; HCV; Liver cirrhosis; Outcome; Spontaneous
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