Evaluation of Ascitic Calprotectin Level in Diagnosis of Spontaneous Bacterial Peritonitis in HCV Egyptian Patients with Liver Cirrhosis and Its Outcome | ||
| The Egyptian Journal of Hospital Medicine | ||
| Volume 100, Issue 1, July 2025, Pages 3942-3949 PDF (642.78 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2025.411867.1815 | ||
| Authors | ||
| Abd-allah Bahnacy1; basma hussieny* 2; Abdel-Naser Abdel-Atty Gadallah3 | ||
| 1Gastroenterology and Hepatology department, Faculty of Medicine, Menoufia University | ||
| 21Gastroenterology and Hepatology department, Faculty of Medicine, Menoufia University. | ||
| 3Internal Medicine, Gastroenterology, Hepatology & Endoscopy department, Faculty of Medicine - Menoufia University, Shebin Elkom, Menoufia, Egypt | ||
| Abstract | ||
| Background: A dangerous side effect of cirrhosis, particularly in people with hepatitis C, is spontaneous bacterial peritonitis (SBP). A diagnosis made early is essential for better results. As a potential diagnostic marker for SBP, ascetic calprotectin has demonstrated promise. Objective: This study aimed to assess ascetic calprotectin levels in the diagnosis of SBP and its consequences in liver cirrhosis patients with HCV in Egypt. Methods: This was a case-control hospital-based study on 120 cirrhotic Egyptian patients with ascites with different demographic data presented to the Hepatology Department of Shebin El-Kom Teaching Hospital and the Internal Medicine Department of Menoufia University Hospitals during the period from March 2023 till June 2024. Results: Logistic regression analysis indicated ascetic calprotectin, ascetic TLC, urea, GFR, albumin and respiratory rate were the most significant independent factors associated with the mortality among the studied patients (p<0.05). While, other variables did not show significant relation with mortality rate (p>0.05). Conclusion: Logistic regression analysis indicated ascetic calprotectin, ascetic TLC, urea, GFR, albumin and respiratory rate were the most significant independent factors associated with the mortality among the studied patients (p<0.05). While other variables did not significant relation with mortality rate (p>0.05). | ||
| Keywords | ||
| Ascetic calprotectin; Bacterial peritonitis; HCV; Liver cirrhosis; Outcome; Spontaneous | ||
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