Efficacy of Hyaluronic Acid Injection Locally on Postoperative Complications after Surgical Removal of Impacted Mandibular Third Molars | ||||
| Dental Science Updates | ||||
| Volume 6, Issue 2, September 2025, Page 263-273 PDF (973.81 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/dsu.2025.298293.1240 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmed Ali Ahmed el sayed emam  1; AMR ALI ELSWEFY2; Mohamed Said Hamed3
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| 1Oral and maxillofacial surgery Faculty of Dentistry suez canal University | ||||
| 2faculty of dentistry , suez canal university | ||||
| 3Department of Oral and Maxillofacial surgery, faculty of dentistry, Suez Canal University | ||||
| Abstract | ||||
| Introduction: Odontectomy is a popular dental surgery treatment. However, nerve injury, bone fractures, delayed healing, inflammation, soreness, edema, and trismus might result. These conditions lower patient quality of life. Many research reduced post impacted tooth surgical problems. Hyaluronan (HA) is a biomaterial that accelerates wound healing. Aim: to evaluate efficacy of Hyaluronic acid injection locally on control of swelling, pain and trismus in surgical removal of impacted mandibular third molars. Patients and methods: This study was a randomized clinical control trial and was conducted on 20 adult healthy patients who required surgical extraction of impacted lower third molar with bilateral, symmetrical lower impacted third molars that need surgical extraction. Each patient has two sides (right and left side) one of them was treated by experimental materials (Group B) and the other side was left without treatment as a control group. Results: The overall difference in VAS was significant according to groups, Time points, and interaction between groups and time). Truisms mouth opening (TMO) in the control group showed an average (±SD) of 40.87±7.97, 29.11±9.88, 34.50±8.55, 40.97±8.18; respectively. However, The TMO in the treated group showed an average (±SD) of 40.87±7.97, 34.50±8.07, 37.80±6.46, and 41.38±7.81; respectively. The linear relationship in TMO with time showed a direct (positive) relationship as revealed by simple linear regression. The mean swelling parameters in the control group showed an average (±SD) of 10.51±0.85, 12.12±0.89, 11.34±0.54, and 10.76±0.58; respectively. However, the mean swelling parameters in the treated group and showed an average (±SD) of 10.51±0.85, 11.24±0.78, 10.64±0.85, and 10.17±0.45; respectively. Regression trendline showing the linear correlation between time and mean swelling parameters. Conclusion: HA injection after extraction of impacted mandibular third molars has a positive effect on postoperative pain, trismus and swelling. | ||||
| Keywords | ||||
| Keywords: Impacted Third Molars; Post-Operative Symptoms; Hyaluronic Acid Injection | ||||
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