Clinical and Radiographic Evaluation of the Effects of Platelet-Rich Fibrin on Treatment Outcomes After Surgical Removal of Impacted Mandibular Third Molar | ||||
Dental Science Updates | ||||
Volume 6, Issue 2, September 2025, Page 301-313 PDF (1.52 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/dsu.2025.349730.1280 | ||||
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Authors | ||||
Adel Fawzy Fadlallah![]() ![]() ![]() ![]() | ||||
1Oral and maxillofacial surgery,Faculty of Dentistry Suez canal University, Ismailia,Egypt | ||||
2Oral and maxillofacial Surgery Department, faculty of Dentistry, Suez Canal University, Ismailia, Egypt. | ||||
3Oral and Maxillofacial Radiology Faculty of Dentistry Suez Canal University, Ismailia, Egypt | ||||
4Oral and Maxillofacial Surgery, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt | ||||
Abstract | ||||
Introduction: Third molar surgical extraction can lead to several complications like pain and edema. Platelet-rich fibrin (PRF) promotes healing, tissue regeneration, and bone growth, offering a cost-effective, biocompatible solution for improved recovery in dental surgeries. Aim: To assess the effect of platelet-rich fibrin on postoperative clinical outcomes and radiographic findings after surgical extraction of impacted Mandibular third molar. Materials and Methods: The present study involved 20 individuals with bilaterally impacted mandibular third molar, aged from 20 to 40 years. The patients were divided into two groups utilizing the split-mouth technique: Group I (Control Group): Included 20 impacted mandibular third molar which were removed, and the extraction sockets were left empty, then the socket was sutured. Group II (Study Group): Included 20 impacted mandibular third molars that were extracted, and the dental sockets were filled with PRF followed by suturing of the sockets. Results: Clinical findings showed significantly lower edema and pain levels in the study group compared to the control group, with no significant difference in maximal mouth opening. Radiographically, bone density increased in both groups over time. Although no significant difference was found at one month between both groups, the study group showed significantly higher bone socket density levels than the control group at four months. Conclusion: Application of PRF following the surgical removal of impacted third molars reduces clinical post-surgical complications as discomfort and edema, in addition, it improves healing and increases bone density of the dental socket. | ||||
Keywords | ||||
Diagora; Mandibular Impacted Third Molar; Platelet-Rich Fibrin | ||||
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