Clinical Efficacy of Chlorhexidine versus Hyaluronic Acid as a Coating on Elastomeric-Ligatures in Managing Gingival and Periodontal Conditions during Orthodontic Treatment | ||||
Dental Science Updates | ||||
Volume 6, Issue 2, September 2025, Page 387-394 PDF (582.8 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/dsu.2025.366077.1294 | ||||
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Authors | ||||
El Sayed Mohamed Awad ![]() ![]() | ||||
1Orthodontics department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt | ||||
2Professor of Orthodontics, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt | ||||
3Lecturer of Oral Medicine and Periodontology, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt. | ||||
Abstract | ||||
Introduction: Keeping a healthy gingival and periodontal environment is an important concern during fixed orthodontic treatment. Chlorhexidine (CHX), being the gold standard, was compared to Hyaluronic acid (HA) which is thought, nowadays, to be a rising agent regarding the healing effects on human tissues, including gingival and periodontal tissues. Aim: The main objective of this trial was the assessment of efficacy of chlorhexidine versus hyaluronic acid as a coating on elastomeric ligatures in managing gingival and periodontal conditions during orthodontic treatment. Materials and methods: Chlorhexidine gluconate and hyaluronic acid 0.88 gels from the same manufacturer (EZ-Pac®) have been applied on plain elastomeric ligatures (Dentaurum®). Three groups of 57 cases in all were created (19 each). Group I received Chlorhexidine (CHX) coated elastomeric ligatures and was called CHX group. Group II received Hyaluronic acid (HA) coated elastomeric ligatures and was called HA group. Group III received plain elastomeric ligatures and was called control group. Recall visits were every month; T0 (pre-appointment assessment), T1 (after one month), T2 (after two months), T3 (after three months). Plaque.index (PI) and gingival.index (GI) have been measured at time intervals; T0, T1, T2 and T3 using Wiliams periodontal probe. Results: A statistically significant drop in PI (0.0381) and GI (P=0.024) was observed in HA than CHX and control group at T3. Conclusion: When compared to chlorhexidine, hyaluronic acid demonstrated a significant reduction in gingival index with a relatively weak correlation between PI and GI in HA group compared to CHX group | ||||
Keywords | ||||
Chlorhexidine; Hyaluronic acid; Gingival Index; Plaque Index; Elastomeric Ligatures; Orthodontics | ||||
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