Multidimensional analysis of factors associated with adherence to HIV medications in Indonesian patients | ||
| The Egyptian Journal of Community Medicine | ||
| Articles in Press, Accepted Manuscript, Available Online from 02 September 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejcm.2025.383396.1402 | ||
| Authors | ||
| Aisyah Lahdji* 1; Chamim Faizin1; Lukman Faishal Fatharani2; Arza Wayustasa3 | ||
| 1Public Health Department, Faculty of Medicine, Universitas Muhammadiyah Semarang, Central Java, Indonesia | ||
| 2Biomedical Sciences Department, Faculty of Medicine, Universitas Muhammadiyah Semarang, Central Java, Indonesia | ||
| 3Faculty of Medicine, Universitas Muhammadiyah Semarang, Central Java, Indonesia | ||
| Abstract | ||
| Background: Patients diagnosed with immunodeficiency virus (HIV) experience a range of impacts, including health, social, economic, and psychological effects. Antiretroviral therapy (ART) is currently the only available treatment for HIV, making adherence to medication essential for effective disease management. Although data on drug resistance in Indonesia is lacking, consistent medication adherence is critical. The objective was to determine patient characteristics, and social factors associate with medication adherence. Methods: Patients with HIV who consented to participate in this cross-sectional study were included using convenience sampling at an outpatient clinic of a general hospital. Three questionnaires were administered in this study: a societal stigma questionnaire, a family support questionnaire, and a medication adherence questionnaire. Results: A total of 218 patients were include. The average age was 42.5±11.0 years and 51.4% were males. Approximately 61.5% of the patients had high medication adherence and 71.1% had adequate family support. All patients were experiencing low to moderate levels of social stigma. In univariate analysis, adherence was associated with male gender, higher income, positive societal stigma, and family support. In multivariate analysis, male patients were 1.8 times more likely to adhere to their medication regimen (aOR= 1.84; p= 0.048), positive societal stigma can increase medication adherence by 2.2 times (aOR=2.17; p=0.011), and family support increases adherence by 2.7 times (aOR=2.73; p=0.005). Conclusions: This study highlights factors associate with medication adherence. HIV programs targeting disease management should focus on improving societal stigma and empowering family support. | ||
| Keywords | ||
| Social factors; HIV; Individual factors; Medication adherence | ||
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