Holter and ECG Changes after Transcatheter Closure of VSD in Children | ||
| The Egyptian Journal of Hospital Medicine | ||
| Volume 100, Issue 1, July 2025, Pages 4323-4328 PDF (440.25 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2025.453497 | ||
| Abstract | ||
| Background: Ventricular septal defect (VSD) is a common congenital heart defect in children, and transcatheter VSD closure is a widely used treatment. However, its impact on cardiac rhythm and conduction remains uncertain, necessitating further evaluation. Aim: To assess the changes in heart rate (HR) and electrocardiographic parameters following transcatheter VSD closure in children, with particular focus on the risk of arrhythmias and conduction abnormalities. Patients and Methods: This prospective observational study was conducted on 76 children diagnosed with VSD who underwent transcatheter VSD closure. Demographic data, medical history, and electrocardiographic parameters were collected before and after the procedure. Pre- and post-procedural 12-lead ECG and Holter monitoring were performed, and follow-up evaluations were conducted at 1 month, 6 months, and 1 year post-procedure. Results: The study found a significant reduction in heart rate (HR) post-procedure, with sustained lower HR at 1 month, 6 months, and 1 year compared to pre-procedural values (P < 0.05). Significant decreases were also observed in RV5, RV5+SV1, and SV1 at 1 month, 6 months, and 1 year (P < 0.05). RR intervals increased significantly post-procedure and at all follow-up intervals (P < 0.05). No significant differences were noted in PR interval, QRS duration, QTc interval, or cardiac axis deviation. Arrhythmic events were rare, with one patient developing complete heart block 1 year post-procedure. Conclusion: Transcatheter VSD closure in children is associated with significant reductions in heart rate and improvements in heart rate variability. However, it does not significantly alter key ECG parameters, and long-term monitoring is important due to the risk of arrhythmias. | ||
| Keywords | ||
| Ventricular septal defect; Transcatheter VSD closure; Electrocardiogram; Holter monitoring; Heart rate variability | ||
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