Studying the effect of Opuntia ficus- indica juice on female rats with fibromyalgia - like condition | ||
| مجلة الاقتصاد المنزلي | ||
| Volume 41, Issue 2, June 2025, Pages 221-246 PDF (647.38 K) | ||
| Document Type: المقالة الأصلية | ||
| DOI: 10.21608/jhe.2025.453787 | ||
| Authors | ||
| Aml F. EL-Gazar; Eman S. Ibrahem; Alaa O.Aboraya; Amr M. El-saied | ||
| Nutrition and Food Sciences Dept., Faculty of Home Economics, Helwan University, Cairo-Egypt | ||
| Abstract | ||
| Background: Fibromyalgia (FM) is a disorder characterized by widespread pain throughout the body, accompanied by other symptoms such as fatigue, sleep, mood disturbances, and cognitive dysfunction. Opuntia ficus-indica widely recognized as prickly pear, it distributed in many areas of the world because of its agronomic, and ecological benefits, besides its large amounts of functional, nutraceutical, and biological activities. Obgective: The main objective of the present study was to investigate the protective effect of Opuntia ficus-indica juice on a fibromyalgia-like condition induced by reserpine in female rats. twenty-five female rats were randomly divided into five equal groups (n=5 rats of each) as follow, negative control group and positive control group were fed only on the basal diet, while groups 3,4 and 5 were fed on basal diet and given orally Opuntia ficus-indica juice OFIJ for the experiential period 8 weeks at a dose of 100, 150 and 200 ml/kg of body weight, for all rats respectively, from the fourth week of the experiential period groups 2, 3, 4 and 5 were injected with reserpine for consecutive 3 days to induce fibromyalgia-like condition. Materials and Methods: the facial expression eye, nose, ear and whisker and analgesic effect of Opuntia ficus-indica on rats were determined, at the end of the experimental period 8weeks, Biochemical analysis was performed to the serum concentration of MDA and antioxidants enzymes. Histopathological of thighs muscles in rats were examined. Results : showed that groups fibromyalgia-like condition female rats , fed on basal diet and given orally Opuntia ficus-indica juice OFIJ had significant improvement of body weight gain, significantly reduced in malondialdehyde MDA while the antioxidants enzymes SOD , GPx , GSH and CAT were significantly increased compared to fibromyalgia-like condition female rats. accompanied by groups fibromyalgia-like condition female rats , fed on basal diet and given orally Opuntia ficus-indica juice OFIJ had a significant improvement Facial expression compared to fibromyalgia-like condition female rats . In addition Histopathological examination showed an obvious improvement in myocytes tissues of fibromyalgia-like condition female rats , fed on basal diet and given orally Opuntia ficus-indica juice OFIJ. Conclusio: Finally, the existing study illustrated that Opuntia ficus-indica juice might improve the fibromyalgia-like condition in rats. | ||
| Keywords | ||
| : Fibromyalgia; Opuntia ficus-indica; antioxidant and Facial expression | ||
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