Erythrocyte/ Reticulocyte Parameters Cut-off Values of Egyptian Adults in Fayoum University Hospital, Egypt | ||
Fayoum University Medical Journal | ||
Volume 15, Issue 3, September 2025, Pages 84-92 PDF (821.83 K) | ||
Document Type: Review Articles | ||
DOI: 10.21608/fumj.2025.349735.1437 | ||
Authors | ||
Yasmeen Mohamed Mahmoud* 1; Eman Mahmoud Ezzat2; Salwa Bakr Mohamed3; Nourhan Mohamed Nasr4; Heba Mostafa Ahmed5 | ||
1internal medicine department faculty of medicine fayoum university | ||
2Internal medicine department, faculty of medicine, fayoum university | ||
3Clinical Pathology department, faculty of medicine, Fayoum university | ||
4Internal medicine department, faculty of medicine, fayoum university | ||
5Clinical Pathology, faculty of medicine, Fayoum university | ||
Abstract | ||
Introduction: Establishing reference values for erythrocyte and reticulocyte parameters is critical for diagnosing and managing hematologic red cell disorders. Aim of the study: To establish the normal cut-off values of erythrocyte/ reticulocyte parameters in Egyptian adults attending Fayoum University Hospital. Subjects and Methods: This cross-sectional research was enrolled 114 apparently healthy Egyptian adults to measure erythrocyte indices and reticulocyte counts using Sysmex XN 1000 automated hematology analyzers. Statistical analysis was performed to define reference ranges and assess sex and age-related variations. Results: The normal cut-off reference values of the factors have been computed with 95% confidence intervals. Gender specific values have been calculated for hemoglobin concentration with a significant difference (p<0.001) (male: 13.50–15.50 gm/dl, female: 12.13–14.7 gm/dl), however, there was no significant difference between gender reference range of Ret-He with a p-value of 0.41. The normal cut-off value of RET-He for discriminating Egyptian adults with functional hemoglobin abnormalities was 30.9 ±2.5 pg. Conclusions: The findings provide a foundation for improved clinical decision-making in diagnosing anemia, bone marrow disorders, and other hematological conditions in Fayoum Governorate. Further larger multicentric studies are recommended. | ||
Keywords | ||
Hematologic; reference; parameters; Ret-He; Egyptian | ||
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