Assessment of healthcare-associated infection of Klebsiella pneumoniae isolated from patients attended private clinics in Basrah governorate | ||
| Microbes and Infectious Diseases | ||
| Articles in Press, Accepted Manuscript, Available Online from 20 September 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mid.2025.409738.3069 | ||
| Authors | ||
| Eiman Ali Saeed* 1; Asmaa Mohammed Hussein2; Sheima Nadim Kadhim2; Qutaiba A. Qasim3 | ||
| 1Department of Clinical Laboratory Sciences, College of Pharmacy, University of Basrah, Basrah , Iraq | ||
| 2Department of pharmacology and toxicology, College of Pharmacy, University of Basrah, Basrah , Iraq. | ||
| 3Department of Clinical Laboratory Sciences, College of Pharmacy, University of Basrah, Basrah , Iraq. | ||
| Abstract | ||
| Background: Occurrence of Klebsiella pneumoniae in patients who attended private clinics poses a threat to increase antibiotics resistance and sporadic transmission, it has acquired a significance similar to that of infections in hospitals and other healthcare facilities. Aim: to highlight Klebsiella pneumoniae, its antibiotics susceptibility pattern, type of resistance, prevalence and frequency in private medical clinics. Methods: 180 clinical samples obtained from urine, blood, sputum, and surgical wounds that subjected to identification and susceptibility analysis by biochemical means, VITEK® 2 and PCR for gene identification. Results: Out of 180 specimen,118 isolates of Klebsiella pneumoniae showed sensitivity to colistin and tigecycline, with high resistance to third-generation of cephalosporins and fluoroquinolones. (77.9%) of multidrug-resistant isolates exhibited production of extended spectrum beta-lactamases (ESBLs), (66%) exhibited carbapenemase activity. The antibiotic resistance genes blaCTX-M was the most commonly observed among other detected resistance genes. Conclusion: Based on the frequency of infection of patients attending private medical clinics with Klebsiella pneumoniae, attention must be paid to this pathogen demonstrates resistance to beta-lactams along with carbapenems and additional antibiotic groups. | ||
| Keywords | ||
| Healthcare-associated infections; private clinics environment; MDR Klebsiella pneumoniae; ESBL; Carbapenemase | ||
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