Staged Hair Transplantation in Face and Scalp Scars after Carbon Dioxide Laser or Platelets Rich Plasma-Assisted Scar Tissue Remodeling
(2025). Staged Hair Transplantation in Face and Scalp Scars after Carbon Dioxide Laser or Platelets Rich Plasma-Assisted Scar Tissue Remodeling. EKB Journal Management System, 100(1), 4397-4406. doi: 10.21608/ejhm.2025.454569
. "Staged Hair Transplantation in Face and Scalp Scars after Carbon Dioxide Laser or Platelets Rich Plasma-Assisted Scar Tissue Remodeling". EKB Journal Management System, 100, 1, 2025, 4397-4406. doi: 10.21608/ejhm.2025.454569
(2025). 'Staged Hair Transplantation in Face and Scalp Scars after Carbon Dioxide Laser or Platelets Rich Plasma-Assisted Scar Tissue Remodeling', EKB Journal Management System, 100(1), pp. 4397-4406. doi: 10.21608/ejhm.2025.454569
Staged Hair Transplantation in Face and Scalp Scars after Carbon Dioxide Laser or Platelets Rich Plasma-Assisted Scar Tissue Remodeling. EKB Journal Management System, 2025; 100(1): 4397-4406. doi: 10.21608/ejhm.2025.454569

Staged Hair Transplantation in Face and Scalp Scars after Carbon Dioxide Laser or Platelets Rich Plasma-Assisted Scar Tissue Remodeling

The Egyptian Journal of Hospital Medicine
Volume 100, Issue 1, July 2025, Pages 4397-4406    PDF (920.41 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2025.454569
Abstract
Background: Thin epidermis, absence of vasculature, and, in rare cases, subcutis all make cicatricial alopecia hair transplantation a challenging procedure. Subcutis is required to support the grafts and provide nutrients to the transplanted follicles.
Objective: This study aimed to better understand how to treat alopecia with hair transplants by comparing the effectiveness of platelet-rich plasma (PRP) injections and carbon dioxide laser therapy in reshaping scar tissue on the scalp and face.
Patients and Methods:  This prospective cohort study was carried out on sixty Egyptian patients with stable cicatricial alopecia, aged from 12 to 35 years, of both sexes, with the following clinical criteria of large surface area of alopecia with weak donor zone, keloids and hypertrophic scars, scars with minimal sub-cutaneous tissue thickness, and immature scars. Patients were followed up for 12 months. Cases were divided into two equal groups: Group A underwent hair transplantation by the FUE technique after scar bed preparation with platelet-rich plasma, and Group B underwent hair transplantation by the FUE technique after one or two sessions of CO₂ fractional laser.
Results: Regarding operative time and histopathological findings, comparison between baseline and post-treatment in both groups revealed highly significant differences (P < 0.001).
Conclusions: Scar preparation is vital for improving transplantation outcomes, whether by PRP or by fractional CO₂ laser.
 
Keywords
Staged Hair Transplantation; Face and Scalp Scars; Carbon Dioxide Laser; Platelets Rich Plasma; Assisted Scar Tissue Remodeling
Supplementary Files
Statistics
Article View: 73
PDF Download: 39