Cervical Cerclage versus Progesterone for Preventing Preterm Birth and Their Outcome in Patients with History of Preterm Labor | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 5, May 2025, Pages 180-185 PDF (291.04 K) | ||
| Document Type: Original Article | ||
| DOI: https://doi.org/10.21608/aimj.2025.446575 | ||
| Authors | ||
| Farid Hassan Ibrahim1; Mohamed Ahmed Abd El Moaty2; Loay Fayez Yehia* 3 | ||
| 1Professor of Obstetrics & Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 2Lecturer of Obstetrics & Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 3MBBCh, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Background: An enormous public health burden has resulted from preterm delivery, which is still a major contributor to the worldwide waste of human resources in the form of premature infants. Objective: In order to determine whether the use of progesterone injections once weekly or the implantation of a preventative cervical cerclage increases the duration of a singleton pregnancy in women who are at high risk of miscarriage due to a history of complications, an ultrasound finding of a "short cervix," or other physical examination findings. Methods: Using inclusion and exclusion criteria, a prospective randomized controlled comparative study involving 100 pregnant women with a history of preterm labor was carried out at tertiary care hospitals in the UAE from June 2022 to April 2024. The hospitals in question were Al-Hussein University Hospital, Sayed Galal University Hospital, and Sheikh Zayed Hospital. Results: There is a statistically significant distinction among the groups when it comes to abortion history, but no difference when it comes to patients' comprehensive medical histories or the first visit when it comes to GA and CL. In terms of the first outcome, specifically the Mean GA at delivery, a statistically significant difference was found between the two groups. Conclusion: In high-risk pregnant women with a singleton, a history of spontaneous preterm birth, or a sonographic short cervix during the middle trimester, intramuscular progesterone therapy was more effective than cervical Cerclage in preventing premature delivery and enhancing perinatal outcomes. A non-invasive and straightforward approach, intramuscular 17α-hydroxyprogesterone caproate spares patients and doctors the agony and complications of anesthesia while also saving time and money compared to cervical Cerclage. | ||
| Keywords | ||
| Preterm Birth; Cervical Cerclage; IM Progesterone | ||
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