Thyroid Dysfunction among Pregnant Women and its Effect on Maternal and Neonatal Outcome | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 5, May 2025, Pages 186-190 PDF (370.48 K) | ||
| Document Type: Original Article | ||
| DOI: https://doi.org/10.21608/aimj.2025.446576 | ||
| Authors | ||
| Mohamed Abdel Hakim Rizk1; Mohammad Salah Eldin Hassanin Hassan2; Ahmed El-Sayed Mohamed3; Mohamed Othman Abdel-Majeed Al-Ganainy* 4, 5 | ||
| 1Professor of Public Health and Community Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||
| 2Professor of Obstetrics and Gynecology, Faculty of Medicine for boys, Al-Azhar University, Cairo, Egypt | ||
| 3Assistant Professor of Occupational Health and Industrial Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||
| 4MBBCh, Demonstrator of Public Health | ||
| 5Community Medicine, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Background: For women with a small thyroid reserve, the stress of pregnancy might cause hypothyroidism, either clinically or subclinically. To account for the physiological changes in thyroid function during pregnancy, reference ranges of TSH or free thyroxine (fT4) derived from non-pregnant populations are adjusted for pregnant women. Aim and objectives: To explore whether or not women with thyroid dysfunction had similar pregnancy outcomes as women without such a problem. Subjects and methods: Using 120 pregnant women enrolled between December 2023 and January 2025, researchers at Al-Azhar University Hospitals (Al-Hussein and Bab Al-Sheria) randomly assigned 40 to an exposed group and 80 to a non-exposed group. Results: When it came to neonatal outcomes, such as Apgar score (5 minutes) and sepsis, the groups were not significantly different. However, when it came to birth weight, neonatal jaundice, respiratory distress syndrome, asphyxia at birth, and NICU admission, there were significant differences. Conclusion: There is a high prevalence of thyroid dysfunction in pregnancy with associated slight adverse short-term effects on both maternal and fetal outcomes. Association of presence of low Birth weight (LBW) babies, low Apgar score, neonatal jaundice, respiratory distress syndrome, birth asphyxia and increased number of NICU admission; is a major finding of this study. | ||
| Keywords | ||
| Thyroid dysfunction; Neonatal outcome; Maternal outcome; Pregnant women | ||
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