NLRP3 Inflammasome Expression and Urinary HSP72 In Relation to Biomarkers of Inflammation and Oxidative Stress in Diabetic Nephropathy Patients | ||
Egyptian Society of Diabetes and Lipidology Journal | ||
Volume 1, Issue 1, October 2021 PDF (119.5 K) | ||
Document Type: Abstracts | ||
DOI: 10.21608/esdlj.2021.455581 | ||
Abstract | ||
Diabetic nephropathy (DN) is one of the major causes of end-stage renal disease. Nod-like receptors nucleotide-binding domain and leucine-rich repeat pyrin-3 domain (NLRP3 (inflammasome displays a considerable role in the chronic inflammatory state observed in diabetic patients. Urinary heat shock protein 72 (uHSP72) is a sensitive and specific biomarker for the early detection the acute kidney injury. | ||
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