Insulin Autoimmune Syndrome | ||
| Egyptian Society of Diabetes and Lipidology Journal | ||
| Volume 5, Issue 1, April 2025 PDF (927.32 K) | ||
| Document Type: Review Article | ||
| DOI: 10.21608/esdlj.2025.456265 | ||
| Abstract | ||
| Insulin autoimmune syndrome (IAS), also known as Hirata disease, was first described by Yukimasa Hirata in Japan in 1970. Disease is a rare endocrine disorder characterized by recurrent attacks of severe hypoglycaemia, characterized by elevated serum insulin, and positive insulin autoantibodies. The diagnosis is very challenging, requiring a careful workup. Early identification and diagnosis of IAS can significantly improve prognosis. Up to now, no standardized guidelines exist for the diagnosis and treatment of IAS. | ||
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